2006. Glycogen synthase kinase-3: an overview of an over-achieving protein kinase. Curr. Drug Targets 7: 1377-1388.Kockeritz, L., B. Doble, S. Patel, and J.R. Woodgett. 2006. Glycogen synthase kinase-3--an overview of an over-achieving protein kinase. Curr Drug Targets. 7:1377-88...
h-prune, which has been suggested to be involved in cell migration, was identified as a glycogen synthase kinase 3 (GSK-3)-binding protein. Treatment of cultured cells with GSK-3 inhibitors or small interfering RNA (siRNA) for GSK-3 and h-prune inhibited their motility. The kinase activity...
Glycogen synthase kinase-3β positively regulates protein synthesis and cell proliferation through the regulation of translation initiation factor 4E-binding ... S Shin,L Wolgamott,J Tcherkezian,... 被引量: 0发表: 0年 Axin, a negative regulator of the Wnt signaling pathway, forms a complex wi...
Glycogen synthase kinase 3 promotes p53 mRNA translation via phosphorylation of RNPC1 来自 Semantic Scholar 喜欢 0 阅读量: 115 作者:M Zhang,J Zhang,X Chen,SJ Cho,X Chen 摘要: The RNPC1 RNA-binding protein, also called Rbm38, is a target of p53 and a repressor of p53 mRNA translation....
Glycogen synthase kinase-3β (GSK3β) is a fascinating enzyme with an astoundingly diverse number of actions in intracellular signaling systems. GSK3β activity is regulated by serine (inhibitory) and tyrosine (stimulatory) phosphorylation, by protein complex formation, and by its intracellular localiz...
Inhibition of glycogen synthase kinase-3: a potential therapeutic target of lithium Jope R. S. ( 2004 ) Inhibition of glycogen synthase kinase-3: a potential therapeutic target of lithium . Clin. Neurosci. Res. 4 , 171 – 179 ... RS Jope - 《Clinical Neuroscience Research》 被引量: 29...
Glycogen synthase kinase-3 (GSK3) regulates many physiological processes through phosphorylation of a diverse array of substrates. Inhibitors of GSK3 have been generated as potential therapies in several diseases, however the vital role GSK3 plays in cell biology makes the clinical use of GSK3 inhi...
Glycogen Synthase Kinase-3 2024 pdf epub mobi 电子书 图书描述 Many researchers believe that GSK-3 and its inhibitors could lead to effective treatments for neurogenerative disorders, type II diabetes, depression and bipolar disorder, and some forms of cancer. This book provides a thorough introducti...
The glycogen synthase kinase-3 (GSK3) family of protein kinases consists of GSK3α and GSK3β isoforms and has a crucial role in multiple cellular signaling pathways. We previously found that GSK3β, a regulator of cell proliferation, is also crucial for cAMP generation and vasopressin-...
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Stabel and et al. 1994. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected ... ...