羟基取代的磺酰脲类是大鼠脑突触体特异性 [3H]glyburide 结合的强效抑制剂。| Hill, RA., et al. 2003. Bioorg Med Chem. 11: 2099-113. PMID: 12670661 格列本脲是一种 K+(ATP)通道阻断剂,在实验性鼠皮肤利什曼病中显示出抗利什曼病活性。| Serrano-Martín, X., et al. 2006. Antimicrob Agents Ch...
Wei H, Löbenberg R. Biorelevant dissolution media as a predictive tool for glyburide a class II drug. Eur J Pharm Sci. 2006;29:45–52.Wei, H, Lobenberg, R (2006) Biorelevant dissolution media as a predictive tool for glyburide a class II drug. Eur J Pharm Sci 29: pp. 45-52...
In the present study, parameters such as solubility, medium pH, surfactant type and dissolution behavior of formulations, influence of sink conditions, stability and discriminatory effect of dissolution testing were studied for the selection of a proper dissolution medium for glyburide (BCS Class II ...
Introduction: Glyburide is a drug for the treatment of diabetes mellitus and has a potential effect on Alzheimer's disease. It is also a BCS Class II drug with low solubility and low permeability. Developing a nanosuspension formulation and increasing the solubility and dissolution rate of ...
Biorelevant dissolution media as a predictive tool for glyburide a class II drug 2006, European Journal of Pharmaceutical Sciences more Hai Wei, Raimar Löbenberg Biorelevant dissolution media as a predictive tool for glyburide a class II drug European Journal of Pharmaceutical Sciences, Volume 29, ...
nausea, diarrhea, upset stomach, and headache Serious side effects of Glyburide-Metformin include: hives, difficulty breathing, swelling of the face, lips, tongue, or throat, swelling, rapid weight gain, shortness of breath, extreme weakness, ...
Established Pharmacologic Class (EPC): Sulfonylurea Initial FDA approval date: 5/1/1984 First FDA applicant: Rx First dosage form: Tablet (oral)Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc...
Scavenger receptor class B type I (SR-BI) and ABCA1 are structurally dissimilar cell surface proteins that play key roles in HDL metabolism. SR-BI is a rec... Nieland,T. J. F - 《Journal of Lipid Research》 被引量: 305发表: 2004年 Placental ABCA1 and ABCG1 transporters efflux chole...
1.25mg/250mg 2.5mg/500mg 5mg/500mg DESCRIPTION GLUCOVANCE ® (GlyburideandMetforminHClTablets)containstwooralantihyper- glycemicdrugsusedinthemanagementoftype2diabetes,glyburideandmetformin hydrochloride. Glyburideisanoralantihyperglycemicdrugofthesulfonylureaclass.Thechemical ...
Drug class sulfonylurea.Indications Management of type 2 diabetes mellitus.IndicationsManagement of type 2 diabetes mellitus.Dosage 1.25 to 20 mg orally once per day or in divided doses.Dosage1.25 to 20 mg orally once per day or in divided doses.Contraindications Hypersensitivity to glyburide or ...