drugsusedinthemanagementoftype2diabetes,glyburideandmetforminhydrochloride. Glyburideisanoralantihyperglycemicdrugofthesulfonylureaclass.Thechemicalnamefor glyburideis1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclo-hexylurea. Glyburideisawhitetooff-whitecrystallinecompoundwithamolecularformulaof ...
Alogliptin is a dipeptidyl peptidase-4 inhibitor under investigation for treatment of patients with type 2 diabetes mellitus. Potential pharmacokinetic (PK) drug-drug interactions of alogliptin with pioglitazone or glyburide were evaluated in healthy adults. In a randomized, 6-sequence, 3-period cross...
Some people with type 2 diabetes also take insulin, sometimes in combination with oral medications. Insulin is also used in "beta-cell failure," a condition in which the pancreas no longer produces insulin in response to elevated blood glucose. This can occur in people with type 2 diabetes. ...
glycemicdrugsusedinthemanagementoftype2diabetes,glyburideandmetformin hydrochloride. Glyburideisanoralantihyperglycemicdrugofthesulfonylureaclass.Thechemical nameforglyburideis1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexy- lurea.Glyburideisawhitetooff-whitecrystallinecompoundwithamolecularfo...
Coadmin- istration of pioglitazone or glyburide and alogliptin: Pharmacokinetic drug interaction assessment in healthy participants. J Clin Pharmacol. 2009;49:1210-1219.Karim A, Laurent A, Munsaka M, Wann E, Fleck P, Mekki Q. Coadminis- tration of pioglitazone or glyburide and alogliptin: ...
GEDEON C,ANGER G,LUBETSKY A,et al.Investigating the potential role of multi-drug resistance protein(MRP)trans- porters in fetal to maternal glyburide efflux in the human placenta[J].J Obstetrics Gynecol,2008,28(5〉:485-489.Gedeon C, Anger G, Lubetsky A, Miller MP and Koren G (2008a)...