细胞内有些tRNA分子的反密码子中含有稀有碱基次黄嘌呤(I),含有I的反密码子在与mRNA中的密码子互补配对时,存在如图所示的配对方式(Gly表示甘氨酸)。下列说法错误的
甘氨酰-tRNA合成酶(Glycyl-tRNA synthetase,GlyRS)是一类结构特殊的酶,在大多数细菌中为α2β2四聚体,而在古细菌、真核生物及少数细菌中为α2二聚体。本研究的结果显示,虽然这两种GlyRS位于α亚基上的催化结构域(CCD)相似,但是它们的反密码子结合结构域(ABD)却存在着很大差别。在进化过程中,由于基因的融合,二...
Here, we report that inositol-requiring enzyme 1α (IRE1α) cleaves the anticodon stem-loop region of tRNAGly(GCC) to produce 5′-tRHs (5′-tRH-GlyGCC) with highly selective target discrimination upon endoplasmic reticulum (ER) stress. Levels of 5′-tRH-GlyGCC positively affect cancer ...
中文: tRNA~(Ala)同功受体的相对含量有变化,其中tRNA_ ~(Ala)增加0%,tRNA_~(Ala)下降%,tRNA~(Gly)同功受体的相对含量无明显变化。英文: The amounts of isoaccepting tRNAAla and tRNAGly in the posterior silkgland of the Eri-silkworm Philosamia cynthia ricini were analysed by selective P-labeling...
tRNA衍生的小RNA (tDRs)广泛分布于血液和尿液等人体组织中,在癌症的进展中发挥着重要作用。然而,tDRs在结直肠癌(CRC)血浆中的表达及其潜在的诊断价值尚未得到系统的探讨。目前有作者发现血浆中5'-tRF-GlyGCC的表达水平是一种很有前景的CRC诊断生物标志物,该研究于2021年2月发布在《Genome Medicine》,IF:10.675。
mRNA分子由一条链组成,tRNA分子由两条链组成 相关知识点: 试题来源: 解析 解:A、mRNA分子上的密码子决定蛋白质的氨基酸序列,A错误;B、转录与翻译都遵循碱基互补配对原则,但是配对方式不完全相同,转录时有T与A配对,翻译时没有,B错误;C、由图可知,甘氨酸对应着3种tRNA,l种氨基酸可以由1种或多种tRNA转运,C...
细胞内有些tRNA分子的反密码子中含有稀有碱基次黄嘌呤(Ⅰ),含有Ⅰ的反密码子在与mRNA中的密码子互补配对时,存在如图所示的配对方式(Gly表示甘氨酸)。下列说法错误的
Even though these genomes have high diversity, an extra copy of tRNA-Gly was presented in all migratory bird-carried V. parahaemolyticus isolates, which could be used as a potentially informative marker of the V. parahaemolyticus strains derived from birds. Antibiotic sensitivity experiments revealed ...
Plant mitochondrial genomes lack a number of tRNA genes and the corresponding tRNAs, which are nuclear-encoded, are imported from the cytosol. We show that specific import of tRNAGly isoacceptors occurs in tobacco mitochondria: tRNAGly(UCC) and tRNAGly(CCC) are cytosolic and mitochondrial, while...
Here, we report a complex structure of the wild-type hGlyRS bound with tRNAGly at 2.95 . In the complex, the flexible Whep-TRS domain is visible in one of the subunits of the enzyme dimer, and the tRNA molecule is also completely resolved. At the active site, a glycyl-AMP molecule ...