LncRNA MNX1-AS1 sustains inactivation of Hippo pathway through a positive feedback loop with USP16/IGF2BP3 axis in gallbladder cancer. Cancer Lett. 2022;547:215862. Article CAS PubMed Google Scholar Guo Y, Li Q, Zhao G, Zhang J, Yuan H, Feng T, et al. Loss of TRIM31 promotes ...
Furthermore, leptin was shown to suppress insulin gene expression,259,260 representing a negative feedback loop. Conversely, insulin enhances ob gene expression and leptin secretion.261–264 Likewise, insulin modulates the expression of adiponectin, another well-known adipokine, the abundance of its ...
Diabetes as a case study of chronic disease management with a personalized approach: the role of a structured feedback loop. Diabetes Res Clin Pract. 2012;98(1):5–10. Article PubMed Google Scholar Billings LK, Doshi A, Gouet D, Oviedo A, Rodbard HW, Tentolouris N, et al. Efficacy...
EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngeal carcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loop. Oncogene. 2016;35(26):3419–31. Article CAS PubMed Google Scholar Yoshida GJ, Saya H. Inversed relationship between CD44 variant ...
We found that the high FSH levels which usually occurred in postmenopausal women induced glucose intolerance, that was previously mainly attributed to decreasing estrogen levels. Serum FSH levels undergo dramatic changes with age due to the loss of negative feedback from inhibin, as well as androgens...
is the difficulty of incorporating negative feedback loops. As discussed above there are difficulties in representing the negative feedback loop regulatingMTH1expression, and it is also impossible to represent Mig1 repression of theMIG1gene. Such auto-repression cannot be included by an AND-relations...
Absorption of monosaccharides is mainly mediated by Na+-d-glucose cotransporter SGLT1 and the facititative transporters GLUT2 and GLUT5. SGLT1 and GLUT2 ar
The app is using the exponetial model from LoopKit. The model takes three paramters: actionDuration, peakActivityTime, and delay. For Novorapid I have set 270, 120, and 15 minutes. I have set on the watch the "back to watch" time for this app to one hour. Like this, it is 1 ho...
To validate that this increase was due to the absence of Irgm1 and not a feedback loop altering IFNg NATURE COMMUNICATIONS | 7:13329 | DOI: 10.1038/ncomms13329 | www.nature.com/naturecommunications 5 ARTICLE NATURE COMMUNICATIONS | DOI: 10.1038/ncomms13329 a Pre-colonization 1 week Wild ...
that of Pdx1cm (OFF-ON; a positive-feedback loop by activating FPidgx. 13gae,bx)p.rMessaifoAnc4m6 from its genomic promoter, which results in sustained high-level MafAg and Pdx1g expression that compensates for the initial lower-level induction by PCREm (day 11; Fig. 3a,b,e–g). ...