参考来源: 1.https://www.fda.gov/news-events/press-announcements/fda-approves-first-cellular-therapy-treat-patients-type-1-diabetes. 2.https://www.prnewswire.com/news-releases/fda-approves-first-cellular-therapy-to-treat-patients-wi...
[5] Vilsbøll, T et al. “Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.” Diabetes vol. 50,3 (2001): 609-13. doi:10.2337/diabetes.50.3.609 [6] Toft-Nielsen, M B et al. “Determinants of the impaired secretion of...
[7]Coskun T,Sloop KW,Loghin C,et al.LY3298176,a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus:from discovery to clinical proof of concept.Mol Metab 2018;18:3-14. [8]Zhang Q,Delessa CT,Augustin R,et al.The glucose-dependent insulinotropic poly...
这意味着艾塞那肽组在改善帕金森病症状方面表现更好。 除此之外,目前世界范围内至少还有两项临床试验正在测试GLP-1药物索马鲁肽作为早期阿尔茨海默病的治疗方法。 从当前的趋势来看,GLP-1药物正在被大力开发其在众多疾病领域中的作用。一个比较重要的...
3.Oral semaglutide 25 mg and 50 mg demonstrate superior reductions in HbA1c and body weight versus 14 mg in people with type 2 diabetes in the PIONEER PLUS phase 3 trial.Notified. 4.The GLP-1R agonist liraglutide limits hepatic lipotoxicity and inflammatory response in mice fed a methionine-...
I., Chiarelli, F., et al. 2007. Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes. Eur J Endocrinol 156:663-671...
GLP⁃１是一种由 30个氨基酸组成的肠促胰岛素激素，餐后由我们人体的回肠远端、结肠近端和迷走神经的L...
参考来源:‘Nassar M, Abosheaishaa H, Chaudhuri A, et al. Assessing the Risk of Recurrence in Acute Pancreatitis Among Patients with Type 2 Diabetes Initiating GLP-1 Receptor Agonists Therapy. Presented at: ENDO 2024; June 1-4, 2024; Boston, MA.’ ...
idiabetes”关注我们, 然后点右上角“…”菜单,选择“设为星标” 编者按: 自GLP-1被发现以来,它已然成为一种“多面手”激素——一个接一个代谢功能被人们发现,远远超出了其作为肠促胰素的经典定义。GLP-1的众多有益的多靶点作用使其逐渐成为更多新兴的治疗领域如脂肪肝、肥胖和神经退行性疾病等的冉冉之“星”药...
I., Chiarelli, F., et al. 2007. Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes. Eur J Endocrinol 156:663-671...