GLP-1 secretion was studied in the mouse enteroendocrine STC-1 cells. Cells were pre-incubated with buffer for 1 h and treated with nutrients: alpha-linolenic acid (αLA), phenylalanine (Phe), tryptophan (Trp), and their combinations αLA+Phe and αLA+Trp with dipeptidyl peptidase...
Shibayagi 胰高血糖素样肽-1(GLP-1)(活性) ELISA试剂盒 胰高血糖素样肽-1(Glucagon-like peptide-1,GLP-1)是胰高血糖素前驱体的一部分。胰高血糖素前驱体于胰脏、小肠下部以及下丘脑中表达。该前驱体的构造中含有与糖代谢有关的各种各样的生理活性物质(胰高血糖素,肠高血糖素,胃泌酸调节素,GLP-1,GLP-2...
LBIS®胰高血糖素样肽-1(GLP-1)(活性) ELISA 试剂盒 胰高血糖素样肽-1(Glucagon-like peptide-1,GLP-1)是胰高血糖素前驱体的一部分。胰高血糖素前驱体于胰脏、小肠下部以及下丘脑中表达。该前驱体的构造中含有与糖代谢有关的各种各样的生理活性物质(胰高血糖素,肠高血糖素,胃泌酸调节素,GLP-1,GLP-2...
Search strings such as “name of the medicinal plants and/or SGLT2 inhibitors”, “name of the medicinal plants and DPP-IV inhibitors”, “name of the medicinal plants and GLP-1 secretion”, “name of the medicinal plants and GLP-1R agonist” were used in this case. ChemDraw was used ...
Desulfovibrio-derived H2S is found to inhibit mitochondrial respiration and induce the unfolded protein response in intestinal L cells, thereby hindering GLP-1 secretion and gene expression. Remarkably, blocking Desulfovibrio and H2S with an over-the-counter drug, bismuth subsalicylate, improves GLP-1...
胰高血糖素样肽-1(Glucagon-like peptide-1,GLP-1)是胰高血糖素前驱体的一部分。胰高血糖素前驱体于胰脏、小肠下部以及下丘脑中表达。该前驱体的构造中含有与糖代谢有关的各种各样的生理活性物质(胰高血糖素,肠高血糖素,胃泌酸调节素,GLP-1,GLP-2)的氨基酸序列。根据表达部位加工酶的特异性,胰脏主要分泌胰...
Glucagon-like peptide 1 (GLP-1) and cholecystokinin (CCK) are gut-derived peptide hormones known to play important roles in the regulation of gastrointestinal motility and secretion, appetite, and food intake. We have previously demonstrated that both GLP-1 and CCK are produced in the endocrine ...
GLP-1 is an incretin hormone that stimulates insulin secretion and forms the basis of a drug class for type 2 diabetes treatment. However, half-life of native GLP-1 is within 2 min in vivo, which is due to degradation by the DPP-4 [18], it is hard to define rapid change after ...
Glucagon-like peptide 1 (GLP1), which is mainly processed and cleaved from proglucagon in enteroendocrine cells (EECs) of the intestinal tract, acts on the GLP1 receptor in pancreatic cells to stimulate insulin secretion and to inhibit glucagon secretion. However, GLP1 processing is not fully un...
Potential roles of glucagon-like peptide-1 and its analogues in dementia targeting impaired insulin secretion and neurodegeneration. Degener. Neurol. Neuromuscul. Dis. 12, 31–59 (2022). CAS PubMed PubMed Central Google Scholar Colin, I. M., Szczepanski, L. W., Gérard, A. C. & Elo...