Glioma is the most common primary intracranial tumor in adults, with high incidence, recurrence, and mortality rates [1]. Overall, the broad category of gliomas (ICD-O-3 histology codes 9380–9384 and 9391–9460) represents approximately 24.5% of all primary brain tumors and 80.9% of all mal...
Glioma is among the most aggressive human malignancies, causing significant human mortalities each year1,2,3. In the clinical practices, gliomas are commonly diagnosed at late/advanced stages with extremely poor prognosis3. Molecularly targeted therapies are essential for better glioma prognosis4,5,6....
TROY is a component of the Nogo receptor complex and plays the key role in neuronal survival, migration, and differentiation. Here, we show the up-regulation of TROY in human glioma tissues and cells. Inhibition of TROY expression slowed glioma developme
Glioma is the most common primary intracranial tumor in adults, with high incidence, recurrence, and mortality rates [1]. Overall, the broad category of gliomas (ICD-O-3 histology codes 9380–9384 and 9391–9460) represents approximately 24.5% of all primary brain tumors and 80.9% of all mal...