Secondary glioblastoma.This type usually develops from a low-grade glioma – a type of tumor found in the brain or spinal cord. It’s more likely to affect younger people, and it’s usually in the frontal lobe of the brain. The survival rate for this type tends to be better than for ...
background Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal.The current standard of care for newly diagnosed glioblastoma is surgical resection tothe extent feasible, followed by adjuvant radiotherapy. In this trial we compared radio-therapy alone with radiotherapy ...
Glioblastoma, brain metastases and soft tissue sarcoma of extremities: Candidate tumors for \\{BNCT\\} A. Sauerwein, Glioblastoma, brain metastases and soft tissue sarcoma of extremities: Candidate tumors for BNCT, Appl. Radiat. Isot., 2014, 88, 46-49... A Wittig,RL Moss,WAG Sauerwein - ...
Resistance to therapeutic use of retinoids in glioma has been observed for over 20 years; however, the exact mechanism of resistance remains unknown. To understand retinoic acid resistance in glioma, we studied the turnover mechanism of retinoid receptor
Recent longitudinal studies of glioblastoma (GBM) have demonstrated a lack of apparent selection pressure for specific DNA mutations in recurrent disease. Single-cell lineage tracing has shown that GBM cells possess a high degree of plasticity. Together
Glioblastoma (GBM) possesses glioma stem cells (GSCs) that exhibit aggressive invasion behavior in the brain. Current preclinical GBM invasion assays using mouse brain xenografts are time consuming and less efficient. Here, we demonstrate an array of methods that allow rapid and efficient assaying of...
and a single case of giant cell glioblastoma multiforme (monstrocellular glioma) of the optic chiasm were stained for AgNORs and counted in a masked fash... MA Burnstine,LA Levin,DN Louis,... - 《Brain》 被引量: 22发表: 1993年 Glioblastoma Multiforme of the Optic Nerve: Report of a ...
Glioblastoma, the most aggressive primary brain tumor, thrives in a microenvironment of relative immunosuppression within the relatively immune-privileged central nervous system. Despite treatments with surgery, radiation therapy, and chemotherapy, prognosis remains poor. The recent success of immunotherapy in...
Glioblastoma, the most common malignant primary brain tumor in adults is a devastating diagnosis with an average survival of 14–16 months using the current standard of care treatment. The determination of treatment response and clinical decision making is based on the accuracy of radiographic asses...
Toxicity tests involving intracranial injection of immunocompetent and immunodeficient mice showed a dramatic reduction in vector toxicity compared to unregulated control virus. Moreover, ICP4-miR124t-injected animals showed a loss of viral DNA in the brain over time, whereas an increase was observed...