For elderly patients with poor KPS, reasonable options include best supportive care, TMZ alone, hypofractionated RT alone, or whole brain RT for symptomatic patients needing to start treatment urgently. Given the balance between short survival and quality of life in this patient population, ...
摘要原文 Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults. Current treatment options at diagnosis are multimodal and include surgical resection, radiation, and chemotherapy. Significant advances in the understanding of the molecular pathology of GBM and associated cell...
Glioblastoma: Multidisciplinary treatment approaches By Luis Moreno Sánchez, MD ImagesGlioblastoma, also known as glioblastoma multiforme (GBM), is the most common and most malignant primary tumor of the central nervous system (CNS) (Figure 1). According to the Central Brain Tumor Registry of the ...
Blurred vision Balance problems Weakness on one side of the body Memory and/or speech difficulties Treatment Options Treatment options for GBM vary depending on a number of factors—tumor size, position, whether it has spread to other regions of the brain and the overall health of the patient....
Cognition: Medical treatment to prevent or treat cognitive decline in brain tumor patients is not recommended. However, cognitive rehabilitation has modest positive effects and should be considered, especially in young glioma patients with relatively favorable prognosis. Since the 2017 EANO guidelines, ...
Glioblastoma multiforme is the most common type of primary brain cancer. Current treatments with surgery, radiation, and chemotherapy are less successful against brain cancers than against other types of cancer. Research is in progress to improve treatment options and prognoses. ...
Glioblastoma (GBM) , also known as glioblastoma multiforme, is the most common and lethal primary brain tumor which exhibits clinical, radiological and pathological heterogeneity. Based on the fact that the incidence has been documented to be constant in various reports, genetic variation is more lik...
astrocytoma (IDH wildtype). GBM is the most aggressive and most common primary brain tumor. Glioblastoma spreads quickly and invades other parts of the brain, with tentacle-like projections, making complete surgical removal difficult. It is common for GBMs to recur after initial treatment. ...
Glioblastoma (GBM) is the most aggressive and common malignant primary brain tumor; however, treatment remains a significant challenge. This study aims to identify drug repurposing or repositioning candidates for GBM by developing an integrative rare disease profile network containing heterogeneous types of...
Glioblastoma multiforme is an aggressive type of brain tumor for which new and better treatment options are urgently needed.