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The compounds with the highest binding affinity, as ranked through a docking score, were synthesised and screened for their ability to inhibit the production of UDP‐GlcNAc. A glycofused oxazoline analogue showed good inhibition, and gave significant results in vitro....
机译:GlcNAc-6P水平调节大肠杆菌的卷曲纤维的表达。 代理获取 页面导航摘要 著录项 相似文献 摘要 Curli are extracellular surface fibers that are produced by many members of the Enterobacteriaceae and contribute to biofilm formation. The environmental cues that promote biofilm formation are poorly understood....
一种谷氨酸棒杆菌内源GlcNAc6P磷酸酶及提高GlcNAc产量的方法专利信息由爱企查专利频道提供,一种谷氨酸棒杆菌内源GlcNAc6P磷酸酶及提高GlcNAc产量的方法说明:本发明公开了一种谷氨酸棒杆菌内源GlcNAc6P磷酸酶及提高GlcNAc产量的方法,具体涉及采用重组...专利查询请上爱企
Design, Synthesis and preliminary biological evaluation of GlcNAc-6P Analogues for the Modulation of Phosphoacetylglucosamine Mutase 1 (AGM1/PGM3)Glycomimeticsenzymatic inhibitorsAGM1dockingantitumor drugsA library of GlcNAc-6 or 1P analogues was designed and each compound was computationally evaluated ...
Design, Synthesis, and Preliminary Biological Evaluation of GlcNAc-6P Analogues for the Modulation of Phosphoacetylglucosamine Mutase 1 (AGM1/PGM3)GlycomimeticsCarbohydratesEnzymesInhibitorsDrug designComputational chemistryA library of GlcNAc 6- or 1-phosphate analogues was designed, and each compound was ...
Relaxation kinetics of the nanoencapsulated F mutant in T conformation: effect of GlcNAc6P concentration.Sergio ZonszeinLaura I. ÁlvarezAñorveRoberto J. VázquezNúñezMario L. Calcagno
Kinetics of the reaction catalyzed by EcGNPDA nanoencapsulated in the T conformation at variable GlcNAc6P concentration.Sergio ZonszeinLaura I. ÁlvarezAñorveRoberto J. VázquezNúñezMario L. Calcagno
本发明公开了一种谷氨酸棒杆菌内源GlcNAc6P磷酸酶及提高GlcNAc产量的方法,具体涉及采用重组谷氨酸棒杆菌进行发酵生产,该重组谷氨酸棒杆菌过表达了如SEQ ID NO.6所示的氨基酸序列,该蛋白编码GlcNAc6P磷酸酶,能将GlcNAc6P去磷酸化为GlcNAc.本发明通过机器学习的方式鉴定了谷氨酸棒杆菌内源GlcNAc胞内转运蛋白以及内源GlcNAc...