By re-analyzing mass spectrometric data from human embryonic and induced pluripotent stem cells, our study also identified Zinc finger protein 462 (ZNF462) as the first human O-GlcNAc-6-phosphate modified protein. Collectively, the data suggests that O-GlcNAc-6-phosphate is a general post-...
Total protein O-linked β-N-acetylglucosamine (O-GlcNAc) levels, and the regulatory enzymes glutamine-fructose-6-phosphate transaminase 2 (GFAT2), O-GlcNAc transferase (OGT), and O-GlcNAcase (OGA).Dolen...
The crystal structure of the isomerase domain of GlcN-6-P synthase from human pathogenic fungus Candida albicans, in complex with UDP-GlcNAc has been solved recently but it has not revealed the molecular mechanism of inhibition taking place under UDP-GlcNAc influence, the unique feature of the ...