regions probably contribute to many disease phenotypes. Here we describe the Genotype-Tissue Expression (GTEx) project, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues...
④ 因此,了解调节变体的作用及其在其中起作用的组织,对于GWAS基因座的功能解释和对疾病病因学的见解至关重要 ⑤ 基因型组织表达(GTEx)项目旨在通过建立样本和数据资源来解决这一局限性,从而能够研究多种人类组织中遗传变异,基因表达和其他分子表型之间的关系(13)。为了方便每个捐献者收集多个不同的组织,该项目通过器官...
Here we describe the Genotype-Tissue Expression (GTEx) project, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues....
OPEN580volume45|NumBeR6|JuNe2013|naturegeneticscommentary(andeventuallycompletelysequenced),withgenotypingdatalinkedtogenome-widegeneexpressionpatternsacrossawiderangeo tis-suetypes.Initially,thisresourcewouldenabletheresearchcommunitytoper ormacom-prehensivesearch oreQTLs(bothtissue-typespeci icandacrosstissuetypes)an...
Here we describe the Genotype-tissue expression (Gtex) project, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues.* A full list of members and affiliations appears ...
Genotype-Tissue Expression (GTEx) 2012 BRN Symposium February 23, 2012 NHGRI: Jeff Struewing, Simona Volpi and Cathy Ng NIMH: Susan Koester and Roger Little Genotype-Tissue Expression (GTEx) NIH Common Fund (commonfund.nih.gov/gtex) Co-chairs – Eric Green, NHGRI & Tom Insel, NIMH Lead ...
The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humansUnderstanding the functional consequences of genetdoi:10.1126/SCIENCE.1262110American Association for the Advancement of ScienceScience
(GTEx) project: www.gtexportal.org: RNA-SeQCv1.1.8 gene rpkm Pilot V3 patch1.The data was used to analyze how tissue samples are related to each other in terms of gene expression data The data can be used to get insights in how gene expression levels behave in in the different human...
昼夜节律基因表达与年龄和性别的差异 | 近日,一篇发表在国际杂志Science上题为“Sex-dimorphic and age-dependent organization of 24-hour gene expression rhythms in humans”的研究报告中,来自瑞士洛桑联邦理工学院等机构的科学家们通过研究发现了与昼夜节律时钟相关基因表达的年龄和性别差异。文章中,研究人员分析了从...
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