Isles AR (2009) Evolution of genomic imprinting in humans: does bipedalism have a role? Trends Genet 25(11):495–500Isles,A. R. (2009). Evolution of genomic imprinting in humans: does bipedalism have a role? Trends in Genetics, 25(11), 495-500....
Genomic imprinting, DNA methylation, and cancer Opinion. Focuses on the potential role of genomic imprinting in human cancer. Evidence of genomic imprinting in humans and other species; Potential molecul... S Rainier,Feinberg, Andrew P. - 《J Natl Cancer Inst Monogr》 被引量: 376发表: 1994年...
Girardot M, Feil R, Lleres D (2013) Epigenetic deregulation of genomic imprinting in humans: causal mechanisms and clinical implications. Epigenomics 5(6):715–728 Article CAS PubMed Google Scholar Girardot M, Hirasawa R, Kacem S, Fritsch L, Pontis J, Kota SK, Filipponi D, Fabbrizio E,...
A review of the data on the mechanisms and effects of genomic imprinting, an epigenetic phenomenon regulating the development in placentate mammals, is presented. In contrast to the majority of gene loci with biallelic expression, the expression of imprinted loci is monoallelic. In humans and mice...
That method sidestepped the problem of genomic imprinting but presents ethical and practical hurdles if this technology were to ever be considered for humans. Mouse Pups With Same-Sex Parents Bred Using Stem Cells, Gene Editing Of particular interest in the DOHaD field is genomic imprinting, an ...
摘要: Opinion. Focuses on the potential role of genomic imprinting in human cancer. Evidence of genomic imprinting in humans and other species; Potential molecular mechanisms for imprinting; Role of DNA methylation in genetic imprinting.关键词:...
Genomic imprinting in mammals is increasingly being implicated in developmental and pathological processes, but without a clear understanding of its function in normal development. We believe that imprinting has evolved in mammals because of the conflicting interests of maternal and paternal genes in relat...
During domestication, several key agronomic traits such as plant height (PH), diameter of the main stem (DMS), number of nodes (NN), and seed size have been selected on by humans, reflecting morphological change from a perennial woody tree to an annual semi-woody crop (Additional file1: ...
展开 关键词: Germ Cells Animals Humans Chromosomal Proteins, Non-Histone Pedigree Chromatin Assembly and Disassembly DNA Methylation Transcription, Genetic Gene Expression Regulation, Developmental Genomic Imprinting DOI: 10.1530/REP-10-0173 被引量: 119 年份: 2010 收藏...
Here we review recent progress in understanding how epigenetic mechanisms control imprinted gene expression. 展开 关键词: Animals Humans Germ Cells Epigenesis, Genetic Gene Expression Regulation, Developmental Genomic Imprinting Models, Genetic Female Male ...