This phenomenon, termed genomic imprinting, is a result of epigenetic modification of the genomes of male and female germ cells that has occurred in a sex-specific way during gametogenesis. There is a balance between the paternal and maternal effects in a normal embryo; results to date suggest ...
This peculiar expression pattern is the result of genomic imprinting, an epigenetic process by which the male and the female germ line confer a parent-of-origin specific mark (imprint) on certain chromosomal regions. The size of imprinted regions ranges from several kilobases to several megabases....
Additionally, each of these clusters is under the control of a discrete region, termed imprinting control region (ICR, also designated imprinting center or imprinting control element). One critical attribute of imprinted genes is that they must be marked with their parental origin so that the ...
: genetic alteration of a gene or its expression that is inferred to take place from the observation that certain genes are expressed differently depending on whether they are inherited from the paternal or maternal parent called also genetic imprinting, imprinting ...
Genomic imprinting in mammalian development: a parental tug-of-war. Genomic imprinting in mammals is increasingly being implicated in developmental and pathological processes, but without a clear understanding of its functi... T Moore - 《Trends in Genetics》 被引量: 2468发表: 1991年 Role for DNA...
Synonyms Epigenetic DNA methylation ; Gene silencingSynonymsEpigenetic DNA methylation ; Gene silencingEpigenetic DNA methylationGene silencingDefinition Genomic imprinting is a non-Mendelian pattern of inheritance where some genes are silenced, or imprinted, in the sperm or egg, and this silencing is ...
Epigenetic and genetic cis-regulatory elements in diploid organisms may cause allele specific expression (ASE) – unequal expression of the two chromosomal gene copies. Genomic imprinting is an intriguing type of ASE in which some genes are expressed mon
2. The hypothesis on active gene effect is put furward on the basis of the research resultabeut heterusis and cross exporiment,with genetic theory of genomic imprinting. 根据前人的研究和杂交育种实践,结合基因组印迹的遗传理论,提出杂种优势产生的活性基因效应的假说。
1. A mark or pattern produced by imprinting; an impression. 2. A distinguishing influence or effect: Spanish architecture that shows the imprint of Islamic rule. 3. A chemical modification of a gene affecting the gene's expression in offspring. 4. a. A publisher's name, often with the...
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