52. Being a medicinally important herb with therapeutic applications in multiple health conditions, the genome and transcriptome sequencing ofT. cordifoliawas much needed to gain genomic insights into the secondary metabolites production responsible for...
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed from a research tool to a clinical application for the diagnosis and management of tuberculosis and in public health surveillance. This development has been facilitated by drastic drops in cost, advances in technology and...
identify sequence variants (Table1). We used direct genome sequence comparison and PCR-based sequencing strategies to validate the quality of the called single nucleotide polymorphisms (SNPs). Two recently sequenced accessions ofG. barbadensecv. Xinhai 21 (XH21) [22] andG. hirsutumacc.TM-1 [21...
The genome of a male Namibian cheetah from the Cheetah Conservation Fund center (Chewbaaka) was sequenced at high coverage on the Illumina HiSeq2000 platform using a shotgun-sequencing approach. Extracted DNA was used to construct short, medium and long mate-pair libraries (170 bp, 500 bp, ...
Since the publication of the first human reference genome in 2001, sequencing technologies have rapidly evolved, leading to increased throughput and reduced cost. Currently, one can obtain a complete human genome in less than two weeks at a cost of USD ~5000 or less, whereas the human genome ...
The exome-capture sequencing was conducted as previously described [84]. In short, the DNA of each genotype was processed via exome-capture using the Roche-Nimblegen exome-capture probe set [85] and DNA sequencing. The sequences were aligned to the P. virgatum genome assembly v.4.1 (P....
The parameter start indicates from where in the chromosomes the structure was computed. One can see that the structure varies within a chromosome; nevertheless, common structures are found. 1.1. Data The technology of micrococcal nuclease (MNase) digestion combined with highthroughput sequencing (...
In recent years genome-wide association study (GWAS) has become an efficient method to study the association of specific traits with molecular polymorphism [8]. Furthermore, the availability of low-cost genotyping techniques such as genotyping by sequencing (GBS) has helped the identification of lar...
borealis in a manner that confers adaptation to a novel environment. 这些结果表明基因组加倍改变了欧蓍草的特征从而使它适应一个新的环境。 If the human genome were put in a straight line, it would be over six and a half feet long. 若将单一细胞内所有的基因组片段拉成一条直线,那长度将超过6....
Since the publication of the first human reference genome in 2001, sequencing technologies have rapidly evolved, leading to increased throughput and reduced cost. Currently, one can obtain a complete human genome in less than two weeks at a cost of USD ~5000 or less, whereas the human genome ...