Genetics of human cardiovascular disease[ J]. Cell, 2012, 148(6): 1242-1257.Sekar Kathiresan,Deepak Srivastava.Genetics of Human Cardiovascular Disease[J]. Cell .2012(6)Sekar Kathiresan,Deepak Srivastava. Genetics of Human Cardiovascular Disease[J]. Cell . 2012 (6)...
Cardiovascular disease (CVD) is a designation for multiple clinical phenotypes that result from the interaction of genetic variants, lifestyle choices, and environmental exposures. This article points to the utility of assessing a person's family history of CVD, which is the sum of genetic factors...
However, many studies examining the genetic basis for cardiovascular disease fail to consider sex as a variable in the study design, in part, because there is an inherent difficulty in studying the contribution of the sex chromosomes in women due to X chromosome inactivation. This paper will ...
Impact of genetic risk score on the association between male childlessness and cardiovascular disease and mortality Angel Elenkov , Olle Melander & Aleksander Giwercman Article 12 August 2021 | Open Access Mapping gene and gene pathways associated with coronary artery disease: a CARDIoGRAM exome...
cardiovascular disease candidate genes (i.e. ATP-binding cassette transporters A1 and C6, peroxisome proliferator activated receptor alpha, interleukin-6); and (3) studies showing that multiple genes appear to be at the intersection of several age-related disorders such as cardiovascular disease, ...
This study found that genetic predisposition to longer telomeres increased risk of multiple cancers but reduced risk for some other diseases, including cardiovascular disease. Article Google Scholar Codd, V. et al. Identification of seven loci affecting mean telomere length and their association with ...
Cardiovascular disease genetics: a long and winding roadOrdovas, Jose M.Abstract Purpose of review: This review has two major goals. The first goal is to raise some of the methodological problems associated with studying the genetics of complex disorders, specifically cardiovascular diseases. The ...
Elevated CRP is a predictor of cardiovascular disease [67, 334], IS risk [328], and forecasts worse functional outcome (mRS) in acute IS patients according to multiple meta-analyses [127, 281]. Heritability estimates of baseline CRP levels range from 10 to 65% [233] and specific genetic ...
Comprehensive suite of genetic tests to inform health decisions Invitae’s tests help you deliver answers in all stages of life. Diagnosis and treatment: cancer, cardiovascular disease, neurology, pediatrics, metabolic disorders & newborn screening, immunology and more Healthy individuals: heritable ...
Accordingly, we included different genes involved in both phases of the immune response to create a list of human genes and genetic variants that are highly likely to be associated with susceptibility to severe COVID-19 disease. This gene list can benefit investigators in two ways: the first ...