Hazardous alcohol consumption: In the past year, participants had scored eight or more on the Alcohol Use Disorders Identification Test (AUDIT), indicating hazardous alcohol consumption. Self-harm: Participant said they had purposely hurt themselves in some way in their lifetime. Penetrative sex bef...
et al. Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nat. Neurosci. 22, 1617–1623 (2019). Article PubMed PubMed Central Google Scholar Tachmazidou, I. et al. Identification of new therapeutic targets for osteoarthritis through genome-wide ...
the number of genetic counseling jobs has doubled since 2010. Students are recruited for positions before they have graduated. The averagestartingsalary for a genetic counselor right out of school is $12K a year greater than theentire profession’s average...
In fact, according to the book, “Occupation and Disease: How Social Factors Affect the Conception of work-Related Disorders” by Allard Dembe, it wasn’t until about WWI when the US passed the major worker’s compensation laws that back pain was considered to be a result of trauma, meanin...
However, no further explorations have been undertaken to characterize Lingo-1 associations with other disorders. We previously provided the first study reporting higher protein levels of Lingo-1 in the dorsolateral prefrontal cortex (DLPFC), a critical region for learning and memory processes, in ...
(herein referred to as all-cause dementia), based on criteria from the Diagnostic and Statistical Manual of Mental Disorders (4th ed.) [17]. Clinical and test data were then sent to the WHIMS Clinical Coordinating Center for central adjudication of final diagnosis by a clinical panel with ...
"There has never been a more exciting time in our field of genetic and genomic medicine, with new approaches to prevention, diagnosis, and treatment of rare and common disorders,” Bruce R. Korf, MD, PhD, FACMG, president of the ACMG Foundation, said in a statement. “The need f...
Several transcription factors used in this study (for example, Cux1, Fezf2, Tbr1, Tbr2 and Foxp2) continue to evolve and diverge in primates44 and are implicated in developmental disorders such as autism23,35. Our transcription factor driver lines provide handles to track the developmental traj...
Developmental Brain Disorders Laboratory, Université de Paris, Imagine Institute, INSERM UMR 1163, Paris, France Marlène Rio Bioinformatics Institute (BII), A*STAR, Singapore, Singapore Chun Teck Lim, Birgit Eisenhaber & Frank Eisenhaber Genome Institute of Singapore (GIS), A*STAR, Singapore, Sin...
Idiopathic scoliosis (IS) is a complex 3D deformation of the spine with a strong genetic component, most commonly found in adolescent girls. Adolescent idiopathic scoliosis (AIS) affects around 3% of the general population. In a 5-generation UK family, l