Since 1950 treatments have been developed to modify the natural history of the disease, the biochemical basis of purine biosynthetic systems have been elucidated, and in the past several years, some causes of gout have been defined at the molecular level. Despite these accomplishments, the ...
Get information about the types of Gaucher disease, a genetic disorder, as well as the causes, symptoms, treatment, and inheritance pattern of this genetic disorder.
Management of crop diseases through disease resistance is acknowledged to be the most desirable and profitable approach. In order to develop cultivars with built-in resistance, the knowledge about the methods of assessing the levels of resistance to diseases caused by microbial pathogens and identifying...
Genetic Causes of Male Infertility November 1, 2021 Almost 10% of couples worldwide struggle with infertility. Learn more about your genetic susceptibility and dig deeper into the lifestyle factors that could affect your sperm. Explore by Symptoms, Supplements, Diet, or Pathway: ...
Gene-gene interactions have long been recognized to be fundamentally important for understanding genetic causes of complex disease traits. At present, iden... X Wan,C Yang,Q Yang,... - 《American Journal of Human Genetics》 被引量: 649发表: 2010年 A Perspective on Epistasis: Limits of Model...
To disentangle these two possible causes of parent-of-origin effects, we assessed the relative impact of the maternal and paternal transmitted and non-transmitted alleles on adult height and birth length for the four parent-of-origin association signals (Supplementary Table 9). This analysis was ...
Gout is among the most common forms of inflammatory arthritis and affects approximately 1 to 6% of the pop- ulation in various countries1–3. An elevated serum uric acid concentration (hyperuricemia, HUA) promotes the deposition of monosodium urate crystals in the joints, which then causes gout...
LNS is also known as "juvenile gout." Some patients can live into their 30s or 40s, but many die before they reach that age. Causes of death include kidney failure, infections which their condition makes them vulnerable to like pneumonia, and injuries resulting from uncontrollab...
All of the study patients had to have received their initial diagnoses of essential hypertension at between 20 and 51 years of age. Furthermore, upon enrollment, the potential causes of secondary hypertension, including chronic renal disease, renal arterial stenosis, primary aldosteronism, coarctation ...
yet its primary causes remain unidentified29. Over the preceding three decades, extensive efforts have been made to determine the factors underlying Taiwan’s high incidence of CKD. Some researchers have suggested the involvement of Chinese herbal medicine30or environmental exposures, such as arsenic31...