Prognostic significance and multidimensional roles of interferon regulatory factors in cancer biology: A comprehensive analysis Guo Ji, ... Zhengyan Chang May 2025View PDF Short communicationOpen access Construction of a prognostic model based on the cuproptosis-related genes in pancreatic cancer ...
which may be causes, consequences or mere correlates of the disease under scrutiny. We propose a method to decompose the observational correlation between gene expression and phenotypes driven by confounders, forward- and reverse causal effects. The bi-directional causal...
cancer biology, immunity and infection, neuroscience, disease-specific animal models, gene and cell-based therapies, and regenerative medicine.Join the conversation about this journal Quartiles 201520162017201820192020202120222023BiochemistryCell BiologyGenetics (clinical)Molecular Biology...
The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis The objective of this study was to examine HLA-DRB1 and HLA-DQB1 genotypes in patients with severe extra-articular rheumatoid arthritis (ExRA) and to compa... C Turesson,DJ Schaid,CM Weyand… - 《...
immune cells and the immune system, and associated processes in the regulation of health and disease. It further highlights articles on the transcriptional and posttranslational control of gene products involved in signaling pathways regulating immune cells, and protective and destructive immune responses....
and cell biology, including but not limited to cell proliferation and apoptosis, signal transduction, stem cell biology, developmental biology, gene regulation and epigenetics, cancer biology, immunity and infection, neuroscience, disease-specific animal models, gene and cell-based therapies, and regenera...
Multiple factors, host and nonhost, influence the susceptibility of individuals and populations to infectious diseases, as well as the severity of the illness once infected.关键词: genetics disease susceptibility infection HIV human mouse DOI: 10.1016/S0749-3797(98)00143-3 被引量: 4 ...
POLYMORPHISMS IN THE ACE2 AND IL-6 GENES AND THEIR POTENTIAL IMPACT ON THE SUSCEPTIBILITY OF SEVERE COVID-19 AMONG ERBIL HOSPITALIZED PATIENTSdoi:10.25271/sjuoz.2024.12.2.1282SARS diseaseCOVID-19 pandemicANGIOTENSIN converting enzymeINTERLEUKIN-6...
(1.58% of cases) is usually associated with disease and may lead to the development of human malignancies [55]. FYN (0.95% of cases) and PRKCA (1.58% of cases) have not been listed as driving genes by CGC, but studies have found that they are associated with many cancers and ...
The molecular processes underlying human health and disease are highly complex. Often, genetic and environmental factors contribute to a given disease or phenotype in a non-additive manner, yielding a gene–environment (G × E) interaction. In this