Because we have recently defined AMPK activation as a key mechanism... X Hou,S Xu,KA Maitland-Toolan,... - 《Journal of Biological Chemistry》 被引量: 1514发表: 2008年 Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Systemic lupus erythematosus (SLE)...
Tang JB,Xu X,Ding F,et al.Expression of genes for collagen production and NF-B gene activation of in vivo healing flexor tendons. The Journal of Hand Surgery . 2004Tang JB,Xu X,Ding F,et al.Expression of genes for collagen produc-tion and NF-kB gene activation of in vivo healing ...
Multiple single-stranded cis elements are associated with activated chromatin of the human c-myc gene in vivo. Transcription activation and repression of eukaryotic genes are associated with conformational and topological changes of the DNA and chromatin, altering t... GA Michelotti,EF Michelotti,A Pu...
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease Genetic association studies have identified 215 risk loci for inflammatory bowel disease1鈥 8, which have revealed fundamental aspects of its molecular biology. We performed a genome-wide ass...
Superoxide dismutases (SODs) are a key antioxidant enzyme family, which have been implicated in protecting plants against the toxic effects of reactive oxygen species. Despite current studies have shown that the gene family are involved in plant growth a
Analysis of single-nucleus RNA-seq of glaucoma-relevant eye tissues reveals that the POAG and IOP colocalizing genes and genome-wide associations are enriched in specific cell types in the aqueous outflow pathways, retina, optic nerve head, peripapillary sclera, and choroid. This study nominates ...
At the cellular level, metabolic abnormalities in inflammatory diseases could be related to the nature of the immune cell infiltrate and its activation status. For example, macrophage polarization is regulated by glycolysis and FAO13, and T cells reallocate glucose and upregulate glycolysis following ac...
Self-report methods are generally the most cost-effective and time-efficient way of obtaining an indication of compliance. In psychiatric research, the most commonly used self-report measure of compliance is the Drug Attitude Inventory (DAI) originally devised by Hogan et al. On the basis of ...
Beta-catenin activation and epithelial-mesenchymal transition in the pathogenesis of pterygium. PURPOSE. To investigate whether β-catenin activation and epithelial-mesenchymal transition (EMT) is involved in the pathogenesis of pterygium. METHODS. β... N Kato,S Shimmura,T Kawakita,... - 《...
Target gene profiling studies and biochemical assays were conducted to follow some of the mechanisms triggered during the somatic-to-embryogenic transition (i.e. dedifferentiation, cell division activation, redifferentiation) and affecting the accessibility of plant cells to receive and stably express the...