Givol. DNA microarray analysis of genes involved in p53 mediated apoptosis: Activation of Apaf-1. Oncogene 20: 3449 – 3455 . 2001 . i0033-7587-160-3-273-b26Kannan,K., Kaminski,N., Rechavi,G., Jakob-Hirsch,J., Amariglio,N. and Givol,D. (2001) DNA microarray analysis of genes...
Downregulation of microRNA-144 inhibits proliferation and promotes the apoptosis of myelodysplastic syndrome cells through the activation of the AKAP12-dep... BACKGROUND :Myelodysplastic syndromes (MDS) represent a family of hematopoietic stem cell disorders characterized by ineffective hematopoiesis. While ...
In recent times, considerable effort has been devoted to understanding how the innate and adaptive immune system perceive and decode various major cell death pathways (like apoptosis, necroptosis, ferroptosis or pyroptosis, amongst others) in dynamic settings of pathologies like cancer and infections. ...
[18] Clauss M, Weich H, Breier G, et al. The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem. 1996; 271(30):17629e17634. [19] Li X, Jin Q, ...
Activation of PPARγ is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in ... Chen, Activation of PPARγ is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in ...
These changes of peripheral nutrient signals activate the NPY/AGRP neurons and attenuate the activity of the POMC/CART neurons, leading to reduced activity of GnRH, GHRH and TRH neurons, and activation of CRH neurons (Shimokawa and Higami, 2001a). These hypothalamic changes result in secretion ...
Acute myocardial infarction (AMI) has two clinical characteristics: high missed diagnosis and dysfunction of leukocytes. Transcriptional RNA on leukocytes is closely related to the course evolution of AMI patients. We hypothesized that transcriptional RN
stimuli, thereby creating a primed state for subsequent stimuli [13,26,27,28]. Evidence points to an association between dynamic DNA methylation changes and acute gene activation following exercise [29]. However, our understanding of epigenetic regulation in response to exercise remains incomplete [...
Alternate reading frame protein (F protein) of hepatitis C virus: paradoxical effects of activation and apoptosis on human dendritic cells lead to stimulation of T cells. PLoS ONE. 2014;9:e86567. PubMed PubMed Central Google Scholar Arazi A, Sharabi A, Zinger H, Mozes E, Neumann AU. ...
6D). Moreover, the NEAT1_2 levels in rotenone group also showed a higher trend and could be rescued by the liproxstatin-1 (Fig. 6E). We next determined the effects of stimulating the α-syn activation in rotenone models. The results showed that in comparison with control group, the ...