英国新生儿全基因组筛查项目Generation Study首批家庭已招募 近日,在2024年分子病理学协会(AMP)欧洲年会上,英国基因组医学中心(Genomics England)宣布与英国国民健康服务体系(NHS)合作开展的新生儿基因组研究项目——“The Generation Study(世代研究)”已经招募了首批家庭,并计划在今年继续分阶段推广。该研究是英国“新生儿...
ludens. PiggyBac-mediated transformations were used for line establishment in this study due to their high success rates across model and non-model insect species alike46. To alleviate the insertion site-dependent effects on construct performance, we assessed 2 strains for each construct. In the ...
Data sharing not applicable to this article as no datasets were generated or analysed during the current study. References https://www.genomicsengland.co.uk/about-genomics-england/the-100000-genomes-project/. Accessed 26/10/2020. https://www.england.nhs.uk/genomics/nhs-genomic-med-service/. Ac...
The majority of patients presenting with short stature do not receive a definitive diagnosis. Advances in genetic sequencing allow for large-scale screening of candidate genes, potentially leading to genetic diagnoses.The purpose of this study was to discover genetic variants that contribute to short ...
Metagenomics The study of genetic material recovered directly from the primary samples Paired-end reading Sequencer starts reading DNA fragment at one end, finishes this direction at the specified read length, and then starts another round of reading from the opposite end of the fragment Per-base ...
Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study. Lancet Infect Dis, 10(12): 835–844. https://doi.org/10.1016/s1473-3099(10)70222-x Article PubMed Google Scholar Gu W, Miller S, Chiu CY, 2019. Clinical ...
An uncareful choice of the reference assembly version will impact the results of downstream phases; therefore, its selection must be considered in advance on the basis of the study purposes. For example, including alternative haplotypes of hypervariable regions, such as the major histocompatibility comp...
Next-generation sequencing(NGS) techniques provide the rapid,high-throughput and costeffective approach to genomics research,which has profoundly transform... QL Zhang,ML Yuan - 《Acta Entomologica Sinica》 被引量: 19发表: 2013年 Study of the long‐distance migration of small brown planthoppers Laod...
Why choose sequencing for small RNA? Although reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) is used as the gold standard for targeted miRNA analysis, if researchers want to study more than a few miRNAs, small RNA sequencing is the best alternative due to its no...
In this study, we have generated transgene-free canker-resistant C. sinensis cv. Hamlin lines via Cas12a/crRNA RNP transformation of embryogenic citrus protoplasts by editing the coding region of canker susceptibility gene CsLOB1. Canker resistance resulting from editing the coding region of canker ...