Transductionis a mechanism which transfersDNAfrom onebacteriumto another bacterium by abacteriophage. Bacteriophage is avirusthat infects and replicates within a bacterium. It is capable of attaching to thebacterial cellwall and injecting its DNA to the bacterium. Inside the bacterium, viral DNA repli...
We selected DAAs for the treatment of HCV because they are a uniquely well-suited technology to be evaluated in a GCEA due to (1) the vast public health impact of this viral disease, supporting the need for a societal perspective and (2) the duration of DAAs on the market, providing evi...
AAV-EF1a-DIO-eYFP (viral titers: 8.3 × 1012 particles/mL) was used as control virus. All of the viruses were purchased from Neuron Biotech (Shanghai, China). For NKCC1 knockdown, the following short-hairpin sequence was used: ACACACTTGTCCTGGGATT. The specificity and efficiency of the ...
GPP-02 II:1 male European 5 yes no no no stress, medication (penicillin, codeine), viral infection prednisolone / yesacitretin / nomethotrexate / yes ciclosporin / yes fever > 38°C: yesmalaise: yesCRP > 100 mg/l: yesESR > 50 mm/hr: yesneutrophilia > 15 × 109/l: yes c.338C...
These models represent the division of the life cycle in various discrete stages and provide explicit connections with the external environment, making them good candidates for decision support system tools. However, despite the current literature offering good theoretical frameworks, most of them lack ...