if the answer is not, we need to do further Protein family, domain, or cluster analysis to clear the relationship between the target sequence and proteins with known structure information.第四,如果不能明确目标序列与相类似的已知序列结构信息之间的关系,或者现有数据库中并不存在与目标序列相似的三维...
General recombination: func- tions and structure of recA protein. Adv. Biophys. 21:135-148.Ogawa, H. & Ogawa, T. (1986). General recombi- nation: functions and structure of RecA protein. Advan. Biophys. 21, 135- 148.General recombination: functions and structure of recA protein. Adv. ...
The β-propeller and thigh domains in αV and the βI and hybrid domains in β8 are resolved in the structure (Fig. 2a, b). The co-crystallized peptide fragment of the TGF-β1 prodomain binds to the interface between the αV β-propeller and β8 βI domain. αVβ8 electron ...
Structural basis of cooperative DNA recognition by the plasmid conjugation factor, TraM. Nucleic Acids Res. Google Scholar Wong and Paranchych, 1976 K. Wong, W. Paranchych The preservation of the secondary structure of R17 RNA during penetration into host bacteria Virology, 73 (1976), pp. ...
If this polypeptide chain continues folding into a substance having a 3D structure,it will be called "protein".{Answer to the second question}:---One deoxyribonucleotide(the unit of DNA) consists of one deoxyribose,one phosphoric acid and one base(Adenine or Cytosine or Guanine or Thymine); ...
amino acid substitutions that we then experimentally screened for improved fitness. To the end user, the algorithm requires only a single wild-type sequence, without any initial binding affinity data, knowledge of the antigen, task-specific supervision, evolutionary homologs or protein structure ...
deconSTRUCT webserver offers an interface to a protein database search engine, usable for a general purpose detection of similar protein (sub)structures. Initially, it deconstructs the query structure into its secondary structure elements (SSEs) and reassembles the match to the target by requiring a...
Methyl side-chain dynamics prediction based on protein structure would allow us to understand the role of side-chain flexibility in different functional processes, such as protein-ligand and protein-protein interactions. ... P Carbonell,AD Sol - 《Bioinformatics》 被引量: 10发表: 2009年 加载更多...
α-Proteobacteria uniquely integrate features of two-component signal transduction (TCS) and alternative sigma factor (σ) regulation to control transcription in response to general stress. The core of this regulatory system is the PhyR protein, which contains a σ-like (SL) domain and a TCS rec...
The Ctc protein of Bacillus subtilis belongs to the general stress proteins. The synthesis of Ctc is controlled by an alternative σ factor of RNA polymerase, σB. Sequence analyses revealed that Ctc is composed of two domains, an N-terminal domain similar to the ribosomal protein L25 of ...