Gene expression in Escherichia coli is controlled by well-established mechanisms that activate or repress transcription. Here, we identify CedA as an unconventional transcription factor specifically associated with the RNA polymerase (RNAP) σ70 holoenzy
Three genesGTF2IRD1,GTF2I, andGTF2IRD2, which encode members of the GTF2I (or TFII-I) family of so-called general transcription factors, were discovered and studied during the last two decades. Chromosome location and similarity of exon–intron structures suggest that the family evolved by...
In Saccharomyces cerevisiae, the large majority of the genes coding for cytoplasmic ribosomal proteins (RPs) depend on the general regulatory factor Rap1 for their transcription, but a small cohort of them relies on Abf1 regulatory activity. A recent study showed that unlike Rap1, whose ...
Define general relativity. general relativity synonyms, general relativity pronunciation, general relativity translation, English dictionary definition of general relativity. n. The geometric theory of gravitation developed by Albert Einstein, incorporat
factor. Other factors include the octamer motifbinding proteins, Oct 1 and Oct2, which also bind to theimmunoglobulin genepromoters (Sturm, Das, and Herr, 1988; Clerc et al., 1988), PEA3 (Polyoma Enhancer A binding protein 3) that was shown to be a member of the Ets family of ...
Big Data (BD) and Artificial Intelligence (AI) play a fundamental role in today’s economy that traditional economic models fail to capture. This paper presents a theoretical conceptualisation of the data economy and derives implications for digital gove
The General Data Protection Regulation, or GDPR, is a comprehensive regulatory framework designed to enhance data privacy standards in the European Union (EU). Since coming into effect in 2018, the GDPR has nearly single-handedly transformed the digit
Depende de diferentes factores recogidos en el reglamento. El artículo 37 del RGPD establece que los controladores y procesadores deberán designar un responsable de protección de datos en cualquiera de estos casos: (a) el procesamiento se lleva a cabo por parte de una autoridad u ...
Recent studies using nuclear magnetic resonance (NMR), together with molecular dynamics (MD) simulations, are beginning to reveal dynamic structures of the general transcription factor TFIIH complexed with target proteins including the general transcription factor TFIIE, the tumor suppressor p53, the cell...
Existing safeguards (encryption,multi-factor authentication) It can be difficult to track down personal data that is scattered throughout the organization’s network in various workflows, databases, endpoints, and evenshadow IT assets.To make data inventories more manageable, organizations can consider ...