Conclusion Under the condition of hepatic and renal fibrosis,increased expression of PRMT1 and decreased expression of DDAH1 in PRMT1 - ADMA - DDAH1 can lead to elevated levels of serum ADMA,cause damages of capillary endothelial cells around hepatic sinusoids and renal tubules,and thus invo...
is not able to improve muscle function in normoxic or chronically ischemic rabbit hindlimbs -role of capillary arterialization and shunting346Effect of PAR-1 inhibition on collateral vessel growth in the murine hind limb model347Quaking is a key regulator of endothelial cell differentiation, neovascul...
The cytotoxicity of GFNs in vitro has been verified in various cells to change the cell viability and morphology, destroy the membrane integrity, and induce DNA damage [110–112]. GO or rGO decrease cell adhesion; induce cell apoptosis; and enter lysosomes, mitochondria, cell nuclei, and endop...
Cancer Treat Rev 14: 319–327 Simionescu M and Simionescu N (1986) Functions of the endothelial cell surface. Annu Rev Physiol 48: 279–293 Simionescu N, Simionescu M and Palade GE (1981) Differentiated microdomains on the luminal surface of the capillary endothelium. I. Preferential ...
oxide generation and cell-cell interactions. Transforming growth factor (TGF)-beta has been described to affect cytoskeletal rearrangement in numerous cell types; however, the underlying pathway is unclear. In the present study, we found that human umbilical vein endothelial cells (HUVEC) have......
MC=mesangial cell, P=podocyte, End=endothelial cell, GBM=glomerular basement membrane, US=urinary space, CL=capillary lumen. FIG. 2. is a panel of immunostaining images and bar graphs showing uPAR is required in podocytes for the development of foot process effacement and proteinuria. (a) The...
Treatment of Ischemic Limbs Based on Local Recruitment of Vascular Endothelial Growth Factor-Producing Inflammatory Cells With Ultrasonic Microbubble Destr... Safety and efficacy of extracorporeal shock wave myocardial revascularization therapy for refractory angina pectoris. Mayo Clinic Proc. 2014; 89 :346...
Finally, there was strong deposition of β-netrin immunoreactivity in the basement membranes of the vascular supply of the brain, as well as in capillary beds throughout the brain; β-netrin mRNA was also detected by in situ hybridization in vascular endothelial cells and the choroid plexus at ...
(prognosis) of sepsis, severe sepsis, and septic shock. Septic shock is the presence of infection associated with a systemic inflammatory response that results in physiologic alterations at the capillary endothelial level, manifesting as a drop in blood pressure. Septic shock can be caused by any ...
Blood Flow Remodels Growing Vasculature During Vascular Endothelial Growth Factor Gene Therapy and Determines Between Capillary Arterialization and Sprouti... For clinically relevant proangiogenic therapy, it would be essential that the growth of the whole vascular tree is promoted. Vascular endothelial gr...