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Development of endocrine resistance in hormone-receptor-positive (HR+ve) subtype and lack of definitive target in triple-negative subtype challenge breast cancer management. Contributing to such endocrine resistance is a protein called CUEDC2. It degrade
Have you ever lacked the time to clone your favorite gene? You should consider gene synthesis, sometimes referred to as synthetic biology. Whether you need industry-leading gene synthesis services or optimized protein expression, or want to outsource the entire process to protein and cell ...
Elsevier India Pvt Ltd.Cell CalciumHirnet D, Olausson J, Fecher-Trost C, Bodding M, Nastainczyk W, Wissenbach U, et al. 2003. The TRPV6 gene, cDNA and protein. Cell Calcium 33 (5–6): 509-518 CrossRef , Medline .Hirnet D, Olausson J, Fecher-Trost C, Bodding M, Nas- tainc...
conclusion can be drawn that the expression level of the heterologous protein secreted by the methylotrophic yeast was higher than that by the other two and the heterologous protein was not overglycosylated.So the methylotrophic yeast showed potential application prospect in the expression of hetero...
Accounting for human polymorphisms predicted to affect protein function. Genome Res. 12, 436–446 (2002). Article CAS PubMed PubMed Central Google Scholar Ramensky, V., Bork, P. & Sunyaev, S. Human non-synonymous SNPs: server and survey. Nucleic Acids Res. 30, 3894–3900 (2002). ...
Endocytosis-like protein uptake in the bacterium Gemmata obscuriglobus Endocytosis is a fundamental process of membrane-trafficking in eukaryotes, but has not been known to occur in bacteria or archaea. The origin of endocytos... TGA Lonhienne,E Sagulenko,RI Webb,... - 《Proceedings of the ...
Mapping these mutations onto the rpoB protein structure revealed that high-level resistance often involves disruption of the interactions with the rigid napthol ring while mutations at positions that contact the ansa bridge had more variable effects, potentially due to increased structural flexibility in ...
ProductPeptide and Protein Technology Almac's peptide and protein technology offering is a key component within our suite of services. We offer a complete range of peptide and protein services from catalogue products through to GMP manufacture from early phase to commercial launch. We have a proven...
The protein ratio was computed from the weighted average of peptide ratios corresponding to each protein; the peptide ratios were differentially weighted based on error factors after bias correction. The detailed formulas for calculation of these values are described in the AB SCIEX manual. In brief...