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By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection. See our privacy policy for more information on the use of your perso...
Dr K. G. Lynch reported receiving grants from the VA OR&D during the conduct of the study, and personal fees from the University of Michigan and Northwell Health outside the submitted work. Dr Shih reported receiving grants from the VA Health Services Research and Development (HSR&D) and ...
Microtome blades were replaced, and equipment was cleaned with RNaseZap (Life Technologies, Paisley, UK) between each block. Sections were immediately transferred to RNase-free 1.5-ml microcentrifuge tubes and placed on ice. RNA was extracted using the RNeasy FFPE kit (Qiagen, Hilden, Germany) ...
8 In addition to creating personal and public health and safety concerns,22 these mood states and behaviors can negatively impact treatment outcome, as emotional distress can con- tribute to drug craving and relapse.23 Given the relevance to abstinence success, therefore, it is important that the...
(2012) Early life stress stimulates hippocampal reelin gene expression in a sex-specific manner: evidence for corticosterone-mediated action. Hippocampus 22:409-420.Gross CM, Flubacher A, Tinnes S, Heyer A, Scheller M, Herpfer I, Berger M, Frotscher M, Lieb K, Haas CA (2012) Early life...
(Meuwissen et al.2001). Using GS has both improved the accuracy of selection and reduced the generation interval. Additionally, GS can provide information on traits that are recorded late in life, or that are difficult or expensive to record (García-Ruiz et al.2016; Hayes et al.2013; ...
EBV and KSHV have methods of either promoting or preventing RIG-I activation, dependent on viral life stage that could contribute to viral persistence and herpesvirus associated cancer progression. 2. Oncogenic γ−herpesviruses control activation of the RNA sensor RIG-I EBV and KSHV have different...
Heart failure (HF) is a life-threatening syndrome characterized by an inability of the heart to meet the metabolic demands of the body. HF costs the US more than $34 billion a year to treat 6 million patients1,2. Despite this, the underlying molecular mechanisms remain poorly understood and...
quality of life[8]. Table 1Oncologic outcomes of TRK inhibitors inNTRKgene fusion positive tumors. Ref. TRKi Sample size Tumor type Objective response rate (%) Duration of response (months) Progression free survival (months) Overall survival (months)...