Hybridization’s Rise to Fame: Recent Advances in Uncovering and Quantifying Gene Flow Although research in some systems has brought insights into the nature of hybridization, detecting and quantifying interspecies gene flow is surprisingly difficult. Until recent advances in sequencing technologies, scienti...
Thus, all genetic information can be seen to flow from the DNA through proteins and, from these, to structure and function. The unit of DNA that contains the information necessary to synthesize a single protein is known as a gene. In higher organisms that have nuclei in their cells (...
A long-standing problem in regulatory genomics is that of predicting gene expression purely from DNA sequence. With a novel transformer architecture, we have made a significant improvement by greatly expanding the receptive field and increasing the information flow between distal elements. In this way...
In the last chapter, no attempt was made to describe how animals mediate patterns of pollen flow within and between plants, nor how efficient various pollination mechanisms are in the dispersal of pollen and in achieving seed-set. The behaviour of pollinators strongly influences pollen flow, and...
Theoretical studies have not differentiated between the effects of genes and chromosomal rearrangements on gene flow, but empirical data suggest that there might be a large difference46,47. In three wild sunflower (Helianthus) hybrid zones (Fig. 1a), for example, rates of introgression were 50%...
from the application in [5]) and set all the p-values larger than 1, after the multiplication, to be equal to 1. Still it should be noted that all the previous options (a,b,c) and also others, like the Log-likelihood-ratio based G-test, could be used during the signal definition...
Horizontal Gene Transfer (HGT) is beneficial to a cell if the acquired gene confers a useful function, but is detrimental if the gene has no function, if it is incompatible with existing genes, or if it is a selfishly replicating mobile element. If the b
(one-tailed). according to definition 2 , if a gene network was built in such ways that every presented edge was a disease-relevant gene-gene interaction, it was a gene network specific to the disease, a sub-network enriched with pathogenic pathways that lead to the disease. in order to...
In animals, the generation of complex body plans from a single cell involves an orchestrated series of patterning events arising from the definition of spatially restricted gene expression territories during development. To study these phenomena, we need a means to chart gene expression in tissue spac...
GFP signal and the shape information of 10,000 cells per biological replicate were recorded, and the.FCS files from the recordings were analyzed using the FlowCore package in R. Cells were filtered based on SSC and FSC, and the first 3000 cell recordings were discarded to avoid cross-well ...