Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in nonprotein coding genes such as rRNA genes or tRNA genes, the product is a structural or hou...
Expression Atlas (http://www.ebi.ac.uk/gxa) is an added value database that provides information about gene and protein expression in different species and contexts, such as tissue, developmental stage, disease or cell type. The available public and controlled access data sets from different so...
After examining mouse, rat and human breast cancer cells, they found that ZBP1 silencing occurs when a methyl group attaches to ZBP1's promoter region (the segment of a gene where gene expression is initiated). The attachment of methyl group prevents the promoter from binding to a protein ca...
confirming that the orientation of promoter elements can influence gene expression79. Surprisingly, the sequencing data also revealed that expression levels were not only influenced by the 3’ GEM-block that was closest to the ORF. Instead, the complete buildup of the 3’ GEM (terminator array...
challenges for targeted delivery and retention of therapeutic proteins due to excess extracellular matrix (ECM). To address this, the authors developed a “Fibrosis Overexpression and Retention (FORT) strategy” that can improve mRNA expression in the fibrotic region and extend the expressed protein ...
Molecular cloning, expression and evolution of the Japanese flounder goose-type lysozyme gene, and the lytic activity of its recombinant protein 来自 Elsevier 喜欢 0 阅读量: 65 作者: HT Aoki 摘要: In this study, we cloned the goose-type (g-type) lysozyme gene from the Japanese flounder ...
Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons. Functional chemokine receptors and chemokines are expressed by glial cells within the CNS, though relatively little is known about the patterns of neuronal... CM Coughlan,CM Mcmanus,M Sharron,...
0102基因差异表达的概念这种差异可能是由于基因序列的变异、表观遗传修饰、环境因素等多种原因引起的。基因差异表达指的是在相同或不同条件下,同一基因在不同细胞或组织中的表达水平存在显著差异的现象。 揭示生物体发育、分化和适应环境的分子机制:基因差异表达研究有助于深入了解生物体在不同生理状态下的基因调控网络...
教程说明综合07 gene expression.pdf,A19CB2 Molecular Biology Part 1B: Regulation of Gene Expression in Eukaryotes An Overview of Gene Expression • Control of gene expression is required for response to – environmental change (e.g. change in type or am
whileMYLK4gene expression and protein levels were significantly increased after the HIIT. Although the function and role of MYLK4 in the skeletal muscle have not yet been elucidated, it is known thatMYLK4is expressed in the human heart, and thatMYLK4expression and protein levels are significantly...