Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced ...
Mechanisms of Gene Regulation ||This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression ...
Regulation of gene expression Regulation of gene expression is a vital process that controls when and how much genes produce proteins. Gene expression is regulated to ensure that proteins are generated in specific cells at specific times. Gene expression is regulated at multiple stages: transcription,...
Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to specific DNA elements to regulate transcription, or mechanisms that modulate translation of mRNA. ...
which may suggest the similar regulatory mechanisms in those two domains (Fig.4a). Because transcription factors play central roles in gene regulation, we further investigated transcription factors in each module, which contained different numbers of co-expressed transcription factors, from 3 (M16) to...
Check out 5 exciting ways to teach Gene Expression & Regulation such as interactive models, games, technology, career exploration, & real-world applications.
These mechanisms ensure that genes are expressed at the correct time and place and that gene products are created at healthy levels. This concept can be conceptualized as how genes are "turned on" or "off" when and where they are needed. Gene regulation can occur during the gene expression ...
The expression of P27, Bcl2, α-TTP, CYP3A, tropomyosin, Il-2, PPAR-γ, and CTGF appears to be up-regulated by one or more tocopherols whereas all other listed genes are down-regulated. Several mechanisms may underlie tocopherol-dependent gene regulation. In some cases protein kinase C ...
During the past year, the characterization of mechanisms and factors capable of disrupting nucleosomes during transcriptional activation has been a recurrent theme in studies which address the contribution of nucleosome structure to gene regulation. In vivo studies using yeast and Drosophila together with...
In prokaryotes, the on–off of transcription serves as the main regulatory control of the gene expression whereas, in eukaryotes, more complex regulatory mechanism of transcription takes place. In addition, RNA splicing also plays a major role in the regulation of gene expression. The primary ...