Mechanisms of genetic regulation in gene expression: examples from drug metabolizing enzymes and transporters. Wiley Interdisciplinary Reviews-Systems Biology and Medicine. 2011; 3:299-313.Mlubb MD,Innocenti F. Mechanisms of genetic-regulation in gene expression:examples from drug metabolizing enzymes and...
Gene Expression Regulation refers to the process by which the human body adjusts the activity of genes in response to changes in nutrient levels. This regulation is controlled by hormones, which monitor the concentration of nutrients in the blood and selectively activate or deactivate specific genes...
Mechanisms of Gene Regulation ||This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression ...
Regulation of gene expression Regulation of gene expression is a vital process that controls when and how much genes produce proteins. Gene expression is regulated to ensure that proteins are generated in specific cells at specific times. Gene expression is regulated at multiple stages: transcription,...
alternative translation initiation, and gene-silencing through microRNAs (miRNAs)—the emphasis (in this chapter) is ongene expression controlat the level of transcription. The transcription process and its overall regulation are reviewed, and main mechanisms through which dietary factors impactgene transcr...
Abstract ΔFosB (a truncated form of FosB) and CREB (cAMP response element binding protein) are transcription factors induced in the brain's reward pathways after chronic exposure to drugs of abuse. However, their mechanisms of action and the genes they regulate remain unclear. Using microarray ...
Cis-acting lncRNAs, which constitute a substantial fraction of lncRNAs with an attributed function, regulate gene expression in a manner dependent on the location of their own sites of transcription, at varying distances from their targets in the linear genome. Through various mechanisms, cis-acting...
Additional Methods of Regulation in Bacteria: Attenuation and Riboswitches Although most gene expression is regulated at the level of transcription initiation in prokaryotes, there are also mechanisms to control both the completion of transcription as well as translation concurrently. Since their discovery...
The molecular mechanisms by which the virus reproduces and alters cell function were previously unknown, and research into SV40 vastly increased biologists' understanding of gene expression and the regulation of cell growth. 这种病毒繁殖与改变细胞功能的分子机制是早已知道的,而且对SV40的研究极大的增加了...
65、riptional Regulation,Control of gene expression usually involves the control of transcription initiation. But gene expression can be controlled after transcription, with mechanisms such as: RNA interference alternative splicing RNA editing mRNA degradation,mRNA transport control,In eukaryotes, trans 66、...