depending on the species, but always involves several changes in the expression of genes that are directly involved in pathways, such as progesterone and oestrogen biosynthesis, immune recognition, membrane permeability, angiogenesis and vasculogenesis, transport of nutrients and signalling for pregnancy rec...
Krieg S. Global alteration in gene expression profiles of deciduas from women with idiopathic recurrent pregnancy loss / Krieg S., Fan X., Hong Y., Sang Q-X., Giaccia A., Westphal L., Lathi R., Krieg A., Nayak N. // Mol Hum Reprod. - 2012. - V. 18. - N 9. - P. 442...
A body of evidence suggests VEGFs regulate critical processes during pregnancy and have been associated with recurrent pregnancy loss (RPL). However, little information is available regarding the interaction of these two major major angiogenesis-related systems in early human pregnancy. This study was ...
The expression of appetite regulation and nutrient response-related genes in the PBMCs of IS mice and in the hypothalamus of their offspring were also affected. In conclusion, this study provides a comprehensive characterization of the PBMCs transcriptome in PPD and suggests that maternal stress may...
Endometrial gene expression profile of pregnant sows with different genetics for neonatal survey The imprinted genes are known to play a critical role in placental development and their expression profiles, in contrast to the endometrium, are well documented. Thus, changes in the expression levels of...
Little is known about the extent of disease, although both isolated STB and a disseminated form of STB have been described. In our Spinal TB X cohort study, we aim to describe the clinical phenotype of STB using whole-body 18FDG-PET/CT, identify a specific gene expression profile for ...
Key words: gene expression / microarray / placenta / pregnancy / sex chromosomes Introduction Females and males of many species demonstrate numerous differences in morphology and physiology, yet they share highly similar genomes. This suggests that the regulation of many sexually ...
Chromatin fragmentation features have previously been explored to infer gene expression profiles from cell-free DNA (cfDNA), but current fragmentomic methods require high concentrations of tumor-derived DNA and provide limited resolution. Here we describe promoter fragmentation entropy as an epigenomic ...
Endometrium has its characteristic DNA methylation profile, although not much is known about the endometrial methylome changes throughout the menstrual cycle. The impact of methylome changes on gene expression and thereby on the function of the tissue, including establishing receptivity to implanting ...
To determine whether the luminal microbiome impacts the metabolic profile of the cervix, we performed PICRUSt2 functional capacity estimates (Fig. 2c; Suppl. Table 3). These results align well with the luminal groups defined by bacterial taxonomic abundance as illustrated in a UMAP analysis (Fig....