Transplant studies and experimental data suggest that a successful pregnancy (SP) depends on the development of a predominant Th2-type immunity profile, while an increase in Th1 cytokines has been associated wit
ORIGINAL ARTICLE https://doi.org/10.5653/cerm.2019.03188 pISSN 2233-8233 · eISSN 2233-8241 Clin Exp Reprod Med 2020;47(1):68-76 The effect of vitamin C on the gene expression profile of sperm protamines in the male partners of couples with recurrent pregnancy loss...
mRNA Sequencing: Discover alternative transcripts, gene fusions, and allele-specific expression patterns with a clear, comprehensive view of the coding transcriptome. Targeted RNA Sequencing: Select and sequence specific genes or transcripts of interest. Profile gene expression for dozens to thousands of ...
The expression of appetite regulation and nutrient response-related genes in the PBMCs of IS mice and in the hypothalamus of their offspring were also affected. In conclusion, this study provides a comprehensive characterization of the PBMCs transcriptome in PPD and suggests that maternal stress may...
“In silico” is an expression used to mean “performed on computer or via computer simulation,” which was used for the biologic pathways, molecular functions, and gene-gene interaction network analysis. Biologic pathways and molecular functions were identified with the use of Toppgene (18) and ...
Chromatin fragmentation features have previously been explored to infer gene expression profiles from cell-free DNA (cfDNA), but current fragmentomic methods require high concentrations of tumor-derived DNA and provide limited resolution. Here we describe promoter fragmentation entropy as an epigenomic ...
Little is known about the extent of disease, although both isolated STB and a disseminated form of STB have been described. In our Spinal TB X cohort study, we aim to describe the clinical phenotype of STB using whole-body 18FDG-PET/CT, identify a specific gene expression profile for ...
Prolonged Application of High Fluid Shear to Chondrocytes Recapitulates Gene Expression Profiles Associated with Osteoarthritis Fei Zhu1, Pu Wang1, Norman H. Lee2, Mary B. Goldring3, Konstantinos Konstantopoulos1,4* 1 Department of Chemical and Biomolecular Engineering, The Johns Hopki...
Dynamic transcriptome changes and increased Hox gene expression induced by RA during neural tube development To define alterations in gene expression profile accompanying RA-induced morphology changes, RNA-Seq was performed on mouse cranial tissue samples from E8.5, E9.5 and E10.5 embryos. Unsupervised...
Endometrium has its characteristic DNA methylation profile, although not much is known about the endometrial methylome changes throughout the menstrual cycle. The impact of methylome changes on gene expression and thereby on the function of the tissue, including establishing receptivity to implanting ...