“gene expression profiling,” the study of the activity of the genes in a cell in a given state. Therefore, studying the cell expression profile can provide insights into its inner cellular processes (e.g., metabolic processes,cell cycle phase, etc.) or the functions it is involved in. ...
Gene Expression ProfileDefinitionDefinitionRefers to the level at which each of a chosen set of cellular genes is expressed, measured as mRNA transcript abundance. To determine an expression profile, messenger-RNA from reledoi:10.1007/978-3-642-16483-5_2367Statistik, Badan Pusat...
Novel antibody-drug conjugates against HER2 are showing high activity in HER2-negative breast cancer (BC) with low HER2 expression (i.e., 1+ or 2+ and lack of ERBB2 amplification). However, the clinical and molecular features of HER2-low BC are yet to be
In many cell biological studies, gene expression is the starting point for elucidation of mechanism at the microscopic and molecular levels, while the gene expression profile is a ‘parts list’ compiled at the macroscopic level. Describing the coordination of gene expression is therefore a central ...
Gene expression profile of gallic acid-induced cell death To reveal the molecular signature of gallic acid-induced cell death, we first identified the genes differentially expressed in the four time point treated samples (GA2hr, GA4hr, GA6hr, GA9hr) relative to the untreated sample (GA0hr)....
A simple plot can be used to show the expression profile for this ORF. Get plot(times, yeastvalues(15,:)) xlabel('Time (Hours)'); ylabel('Log2 Relative Expression Level'); You can also plot the actual expression ratios, rather than the log2-transformed values. Get plot(times, 2...
2. UniGene: refers to predicted gene expression profile delineated by tissue type. 3. Transgenic Cross-Reactivity Check: To check assays for cross-species reactivity for use in transgenic animal experiments, select the species that you do not wan...
Geneexpressionprofileanalysisof theALLcellsdemonstratedsignificantoverlapwithhumanMLL-rearrangedALL. ALL细胞基因表达状况分析表明其与人MLL重排的ALL具有相当的重叠。 ggene.cn 3. Theexperimentalresultsshowthat the proposedapproachcanimprovetheclusterresultsofcancergeneexpressionprofile. ...
We conducted an analysis of tumours from 38 patients with locally advanced HER2-positive breast cancer who had received trastuzumab combined with docetaxel. Quantitative reverse transcriptase (RT)–PCR was used to assess the expression of 30 key genes; microarray analyses were carried out on 25 tumou...
Unlike gene expression profiles from breast cancer that has been reported previously49,50which were determined using cases and control group based on what is called a “workout” which means that the tests are based on control groups with positive findings (abnormal mammograms) and the prevalence ...