在Y的covariance matrix中出现了我们关心的参数 gamma,并且gamma描述的是 cell type A1,A2, B1,B2,所构建的 gene expression contrast (A1-A2, B1-B2) 之间的 pearson correlation coefficient。 这就给我们构建 gamma 的估计 提供了一个锚点: A1, A2, B1, B2,就是RNA-seq data中,gene i在两个物种,四个...
We computed pairwise gene expression correlations27 of 11,130 highly expressed and variable genes across 106 individuals and the 38 identified cell populations (Fig. 3a, Supplementary Fig. 8 and Methods). We identified 12 gene modules that represent key cellular functions involved in T cell ...
We present Correlation AnalyzeR, a user-friendly web interface for exploring co-expression correlations and predicting gene functions, gene–gene relationships, and gene set topology. Correlation AnalyzeR provides flexible access to its database of tissue and disease-specific (cancer vs normal) genome-...
In order to study the correlation of gene and protein expression with specific extracellular protein production rate (SPPR) we grew T. reesei in lactose limited chemostats in three conditions: specific constant growth rates of 0.03 h-1 (D03) and 0.06 h-1 (D06) with 10 g/L of lactose an...
Fig. 3: CLD AT2 cells exhibit baseline differences in gene expression profile coping with viral infection. a Significant gene expression correlation in AT2 cells between TMPRSS2 and ACE2, BSG (CD147) and NPR1 in COPD and IPF samples, each dot represents the average expression level of the g...
not reach the fold-change threshold (Figure5). The enrichment of the Complement and Coagulation cascades KEGG pathway was driven by up-regulation of the proteins KNG1, KNG2, KNG1L1, C4, F2, and FGB, although there was not a complete correlation between transcript/protein expression level and ...
On the other hand, the expression of AS1 in leaves (especially in trifoliate leaves of young seedlings) showed a positive correlation with seed protein contents in the soybean cultivars tested. Therefore, in spite of the fact that the principle transporting compounds in soybean plants for nitrogen...
In the current study we used gene expression correlation analyses to search for DNA-binding transcription factors whose activities might relate to lysosomal function. The strongest candidate that emerged from our data was Stat6, a widely expressed transcription factor that is activated in response to ...
基于基因表达谱(gene expression profile)的成对相关系数(pair-wise correlation coefficient),检测病变类异质性(intralesional heterogeneity)后,结果显示,对比于HSIL、LSIL和正常组,SCC的相关性更弱,其反映SCC病变内呈现分子异质性(Figure 2B)。 成对样本(pairwise samples)的相关性热图(correlation heatmap)显示,无创...
Correlation analyses of gene expression in the somatic embryogenesis stages of tea. (A) Venn diagram of gene expression at different stages of occurrence. (B) Scatter plot of DEGs in different stages. (C) The DEGs cluster heat map between different stages. PS preliminary stage, IS intermediate...