The association of C34T polymorphism of the AMPD1 gene with features of metabolic syndrome in patients with coronary artery disease without heart failureThe common C34T polymorphism in the AMP deaminase-1 (AMPD1) gene results in premature stop codon, and thus, in a an inactive enzyme. Reduced...
Objective To study the association of the polymorphism of HindⅢ site of intron 8 and PvuⅡ site of intron 6 of the lipoprotein lipase(LPL) gene with metabolic syndrome(MS) and insulin resistance(IR) in pilots,so as to provide the basis for preventing MS.Methods The HindⅢ and PvuⅡpolymo...
-drinkers with CT/TT genotype.Conclusion The PPARγ2 gene C1431T polymorphism is associated with metabolic syndrome risk in Kazakh.CC genotype and C allele may serve as genetic risk factors of metabolic syndrome and CC genotype and alcohol drinking may have additive effect on metabolic syndrome....
From the pilot genotyping results, we found that several CD36 gene SNPs were associated with metabolic syndrome status and metabolic trait, including HDL, triglycerides, body mass index, fasting glucose and triglyceride levels (Additional file 1: Table S2). Finally, we selected the 7 SNPs for ...
A functional nonsynonymous toll-like receptor 4 gene polymorphism is associated with metabolic syndrome, surrogates of insulin resistance, and syndromes of... A functional nonsynony- mous toll-like receptor 4 gene polymorphism is associated with metabolic syndrome, surrogates of insulin resistance, and...
In patients with metabolic syndrome, the prevalence was 26.9%, 56.3%, and 16.8%, respectively; in patients without metabolic syndrome, it was 21.6%, 62.7%, and 15.7%, respectively. The angiotensin-converting enzyme insertion/deletion polymorphism was not significantly associated with presence of ...
Maternal–fetal metabolic gene–gene interactions and risk of neural tube defects Single-gene analyses indicate that maternal genes associated with metabolic conditions (e.g., obesity) may influence the risk of neural tube defects (NTDs)... PJ Lupo,LE Mitchell,MA Canfield,... - 《Molecular Gene...
Single-nucleotide polymorphisms in INPPL1 gene are associated with susceptibility to type 2 diabetes and metabolic syndrome in Japanese, Chinese and European populations.23–27 In vitro studies suggested that several of these variants increase SHIP2 levels24,26 or enhance Akt pathway activation,27 ...
Jin, W.et al. Association of MTHFR C677T gene polymorphism with metabolic syndrome in a Chinese population: a case–control study.J. Int. Med. Res.46, 2658–2669 (2018). Li, M. N.et al. MTHFR C677T gene polymorphism and the severity of coronary lesions in acute coronary syndrome.Me...
For the -844 G/A polymorphism, the G/A genotype (OR = 2.79; 95% CI, 1.11-7.08; p = 0.015) and the A allele (OR = 2.2; 95% CI, 1.10-4.43; p = 0.015) were associated with metabolic syndrome. The -844 G/A and A/A genotypes were associated with increase in plasma triglycerides...