Genetic variations inACE2gene associated with metabolic syndrome in southern China: a case–control studyMetabolic syndromeAngiotensin-converting enzyme 2Gene polymorphismObesityGender heterogeneityMetabolic sy
From the pilot genotyping results, we found that several CD36 gene SNPs were associated with metabolic syndrome status and metabolic trait, including HDL, triglycerides, body mass index, fasting glucose and triglyceride levels (Additional file 1: Table S2). Finally, we selected the 7 SNPs for ...
For the -844 G/A polymorphism, the G/A genotype (OR = 2.79; 95% CI, 1.11-7.08;p= 0.015) and the A allele (OR = 2.2; 95% CI, 1.10-4.43;p= 0.015) were associated with metabolic syndrome. The -844 G/A and A/A genotypes were associated with increase in plasma triglycerides level...
Depression (major depressive disorder) is a highly heterogeneous psychiatric syndrome with a weak correspondence to its biological substrates. In large-scale epidemiological studies, the lifetime incidence of depression is two-fold higher in women, such that female sex is among the strongest known risk...
A similar association was found in waist cir- cumference as a more specific parameter of the metabolic syndrome. Accordingly, higher diastolic blood pressure, another component of the metabolic syndrome, was associated with the I128 allele in the MICK (Table 2). For some authors, lower ...
HDL, high-density lipoprotein; LDL, low-density lipoprotein; MetS, metabolic syndrome. Table 5. Relationship between the Alternative Healthy Eating Index (AHEI) and concentrations of plasma lipids among the 2481 participants with metabolic syndrome included in the study Plasma lipidsβ (95% CI), in...
(3) studies on humans identified with disease other than metabolic diseases; (4) randomized controlled trials; (5) gene-vitamin D interaction studies, (6) haplotype studies, (7) studies with outcome as serum 25(OH)D, bone disease, metabolic syndrome, type 1 diabetes, diabetic complications ...
NAFLD is characterized by excess fat accumulation in the liver and is strongly associated with obesity and metabolic syndrome. It has been estimated that ∼25%–30% of the adult population in the U.S. develops NAFLD, which may progress into nonalcoholic steatohepatitis (NASH), a more severe...
Single-nucleotide polymorphisms in INPPL1 gene are associated with susceptibility to type 2 diabetes and metabolic syndrome in Japanese, Chinese and European populations.23–27 In vitro studies suggested that several of these variants increase SHIP2 levels24,26 or enhance Akt pathway activation,27 ...
Many human and mouse studies positively correlates Δ-6 activity with metabolic syndrome, insulin resistance and obesity (reviewed in Naughton et al.25). Diets rich in C18:2 result in an increase in C20:4, which can then be converted into prostacyclins and endocannabinoids, both of them with...