This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and...
Background: This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the de...
Target gene Ct-values (CPA3, GATA2, HDC, MS4A2, TPSAB1/TPSB2) were referenced to household β-actin Ct values as a measure of relative mRNA abundance of the target in each sample. Target/β-actin-ratios in eosinophilic and non-eosinophilic groups determined by microscopy with an ...
This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and...
Can we speculate on the target genes that are regulated at these first stages of thymocyte differentiation by GATA-3? It is well established that the components of the pre-TCR, i.e., TCR β, pΤα, CD3ε, CD3γ, or the RAG genes, are essential for thymocyte development beyond the ...
member of the GATA family of transcription factors that are so named because they bind to the specific nuclear sequence GATA on the promoter and enhancer sites of target genes (T/A(GATA)A/G). GATA2 is highly homologous to GATA3. GATA2 is encoded by the GATA2 gene on chromosome 3q21.3...
背景介绍:this gene encodes a member of the gata family of zinc-finger tranion factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. the encoded protein plays an essential role in regulating tranion of genes involved in the development an...
Third, other regulatory molecules specific to each target gene may function cooperatively with GATA1. If GATA1 is required for the expression of such cofactors, a regulatory network will be formed and relevant gene expression will be delayed. We propose that the stage-specific regulation of ...
Target Protein:GATA2 IR:Immunogen Range:351-450/480 Clonality:Polyclonal Isotype:IgG Entrez Gene:2624 Swiss Prot:P23769 Source:KLH conjugated synthetic peptide derived from human GATA-2:351-450/480 Purification:affinity purified by Protein A ...
Our findings reveal a mechanism of how GATA2 contributes to the high levels of target gene transcription associated with MC identity and robust responsiveness to antigenic stimulation. We demonstrated that the same set of binding motifs of GATA2 and co-TFs PU.1, RUNX1, EGR1 and EGR2 are ...