GAS8-AS1基因检测检测的是人的基因序列变化及表征数据库中标号为750的核酸分子上的碱基序列。它的突序及序列异常会引起正在通过基因解码技术进行收集、查证并编辑,请关注佳学基因,获得及时更新的人类基因序列变化与疾病表征数据库的更新内容。针对基因信息变化所产生的健康问题的靶向药物情况甲状腺乳头状癌 【佳学基因检...
The lncRNA GAS8 antisense RNA 1 (GAS8-AS1, also known as C16orf3) is located in the second intron of GAS8 and has been reported to be both abnormally expressed in several diseases and closely correlated with many clinical characteristics. GAS8-AS1 has been shown to affect many biological...
目的探讨血清miR-451a,miR-25-3p,GAS8-AS1联合用于早期甲状腺乳头状癌的诊断价值.方法纳入2016年3月至2019年3月池州市人民医院收治的早期甲状腺乳头状癌患者70例为肿瘤组,良性结节患者70例为良性组,健康体检者70名为对照组.通过实时荧光定量PCR检测血清miR-451a,miR-25-3p,GAS8-AS1的表达量.通过酶联免疫吸附...
目的 探讨长链非编码RNA(LncRNA)GAS8-AS1在甲状腺微小乳头状癌中的表达变化特点及临床意义.方法 收集70例甲状腺微小乳头状癌(PTMC)患者及24例良性结节患者的新鲜组织标本,采用实时荧光定量PCR(RT-qPCR)技术检测GAS8-AS1的表达差异,分析其表达水平与临床病理特征的相关性.结果 GAS8-AS1在PTMC组织中表达与良性结节及...
GAS8-AS1在食管鳞癌中的表达情况,探究GAS8-AS1对食管鳞癌的作用及其参与的分子机制,为临床诊断,治疗及预后评估提供可靠的理论基础和新的方向.方法首先,通过RNA-seq分析在食管鳞癌及其癌旁组织中差异表达的lncRNA,确认lncRNA GAS8-AS1在食管鳞癌中存在低表达,通过q PCR进一步扩大样本分析确认lncRNA GAS8-AS1在食管...
Lnc RNA GAS8-AS1 inhibits cell proliferation through ATG5-mediated autophagy in papillary thyroid cancer. Qin Y,Sun W,Zhang H.et al. Endocrine . 2018Yuan, Qin,Wei,etc.LncRNA GAS8-AS1 inhibits cell proliferation through ATG5-mediated autophagy in papillary thyroid cancer.[J].2018,(Spec)....
We found that GAS8-AS1 was downregulated in PTC tissues and cell lines. In patients with PTC, low GAS8-AS1 expression was associated with higher tumor-node-metastasis (TNM) stage and lymph node metastasis (LNM). Functionally, GAS8-AS1 significantly promoted autophagy and inhibited PTC cell ...
Whole exome sequencing identifies lncRNA GAS8-AS1 and LPAR4 as novel papillary thyroid carcinoma driver alternations. Pan W,Zhou L,Ge M,Zhang B,Yang X,Xiong X,Fu G,Zhang J,Nie X,Li H,Tang X,Wei J,Shao M,Zheng J,Yuan Q,Tan W,Wu C,Yang M,Lin D. Human Molecular Genetics . ...
目的探讨血清miR-451a,miR-25-3p,GAS8-AS1联合用于早期甲状腺乳头状癌的诊断价值.方法纳入2016年3月至2019年3月池州市人民医院收治的早期甲状腺乳头状癌患者70例为肿瘤组,良性结节患者70例为良性组,健康体检者70名为对照组.通过实时荧光定量PCR检测血清miR-451a,miR-25-3p,GAS8-AS1的表达量.通过酶联...
目的 探讨长链非编码RNA(LncRNA)GAS8-AS1在甲状腺微小乳头状癌中的表达变化特点及临床意义.方法 收集70例甲状腺微小乳头状癌(PTMC)患者及24例良性结节患者的新鲜组织标本,采用实时荧光定量PCR(RT-qPCR)技术检测GAS8-AS1的表达差异,分析其表达水平与临床病理特征的相关性.结果 GAS8-AS1在PTMC组织中表达与良性结节及...