关键词:肝疾病,酒精性;模型,动物;Gao—Binge模型中图分类号:R575 文献标志码:A 文章编号:1001—5256(2019)03—0485—04Application status and future prospect of the Gao—-Binge model in alcoholic liver diseaseZHOU Ke,WANG Hua.(School of Pharmacy,Institute of Liver Diseases,Anhui Medical University,...
GaoBinge模型在酒精性肝病研究领域应用现状及未来前景
This modelis easy to perform, and is time and cost efficient.[Key words] liver diseases, alcoholic; mice; control groups; models, animal[作者单位] 20852 贝塞斯达,美国国立卫生院酒精滥用与酒精中毒研究所肝病实验室(高斌、常彬霞、徐明江);100039 北京,解放军第三〇二医院非感染性肝病诊疗中心(常彬霞)...
Hepatocyte-specific HIF-1β knockout mice were resistant to steatosis and liver injury from the Gao binge model.HongMin NiAmar BhaktaShaogui WangZhenrui LiSharon ManleyHeqing HuangBryan CoppleWenXing Ding
Role of Hypoxia Inducing Factor-1β in Alcohol-Induced Autophagy, Steatosis and Liver Injury in Mice We further found that hepatocyte-specific HIF-1 knockout mice developed less steatosis and liver injury following the Gao-binge model or acute ethanol treatment compared with their matched wild type...
摘要: C3G suppressed hepatic oxidative stress and reduced hepatic lipid accumulation and inflammation.C3G enhanced Parkin-mediated mitophagy.C3G enhanced mitophagy by activating the AMPK pathway.关键词: Cyanidin-3-O-glucoside Alcoholic liver disease mitophagy AMPK pathway ...