Persistent gammaH2AX:A promising molecular marker of DNA damage and aging. Siddiqui M S,Francois M,Fenech M F,et al. Mutat Res Rev Mutat Res . 2015Siddiqui MS, Francois M, Fenech MF, Leifert WR (2015) Persistent γH2AX: a promising molecular marker of DNA damage and aging. Mutat Res ...
40. Bouquet F, Muller C, Salles B: The loss of γH2AX signal is a marker of DNA double strand breaks repair only at low levels of DNA damage. Cell Cycle 2006, 5:1116-1122. 41. Nazarov IB, Smirnova AN, Krutilina RI, Svetlova MP, Solovjeva LV, Nikiforov AA, Oei SL, Zalen...
Radiation can induce DNA double-stranded breaks, which are typically detected by the fluorescence of phosphorylated histone H2AX. In this study, we examined the usefulness of the dynamics of radiation-induced gamma-H2AX foci of peripheral blood lymphocytes (PBLs), as a marker of DNA repair ability...
|[gamma]|H2AX: a sensitive molecular marker of DNA damage and repair Phosphorylation of the Ser-139 residue of the histone variant H2AX, forming gammaH2AX, is an early cellular response to the induction of DNA double-strand ... LJ Mah,A El-Osta,TC Karagiannis - 《Leukemia》 被引量: ...
(2006). The loss of gammaH2AX signal is a marker of DNA double strand breaks repair only at low levels of DNA damage. Cell Cycle 5: 1116-1122.F. Bouquet, C. Muller, B. Salles, The loss of gammaH2AX signal is a marker of DNA double strand breaks repair only at low levels of DNA...
In pre-cancerous cells where DNA damage is induced by deregulated oncogenes, the DNA damage response may serve as a tumor suppressor mechanism.1 It is apparent that a better understanding of the endogenous events that can lead to DNA damage and the following DNA damage response are required ...
marker genes for transcriptome-based phytodosimetry in a monocot plant, rice (Oryza sativaL.), and compared different phytodosimetry models between rice andArabidopsisusing gamma-H2AX, comet, and quantitative transcriptomic assays. The transcriptome-based dose–response curves of four marker genes (Os...
Flow cytometry of the marker of DNA damage response: gamma-H2AX in human osteoblast-like U-2 OS cells on fresh (A) and aged (B) C 60 /Ti composites with various Ti concentrations (low...