利用Cre-LoxP技术构建标记GABA能神经元的转基因小鼠 刘慧\李淑娇2,王瑞青'，蒲雪茵2,李凯峰2,杨雁灵,王路卜，王亚云2’4** (1.延安大学医学院人体解剖与组织胚胎学教研室，延安716000 ; 2.空军军医大学基础医学院基础医学教学实验中心 神经系统线粒体可塑性疾病研究单元，西安710032 ; 3.空军军医大学第一附属...
GABA能神经元Cre-LoxP系统运动协调性小鼠目的:通过Cre-LoxP技术构建转基因小鼠,示踪全脑γ-氨基丁酸(GABA)能神经元分布及形态.方法:使用C57BL/6J-Gad2em1 (IRES-iCre-pA)Smoc小鼠(Gad2-ires-cre小鼠)与B6/JGpt-H11em1Cin(CAG-LoxP-ZsGreen-Stop-LoxP-tdTomato)/Gpt小鼠(B6-G/R小鼠)杂交产生Gad2 tdTomato...
目的:通过Cre-LoxP技术构建转基因小鼠,示踪全脑γ-氨基丁酸(GABA)能神经元分布及形态.方法:使用C57BL/6J-Gad2em1 (IRES-iCre-pA)Smoc小鼠(Gad2-ires-cre小鼠)与B6/JGpt-H11em1Cin(CAG-LoxP-ZsGreen-Stop-LoxP-tdTomato)/Gpt小鼠(B6-G/R小鼠)杂交产生Gad2 tdTomato/non-Gad2ZsGreen子代小鼠,使用CatWalk步...
基于Cre-LoxP技术新建Gad2~(tdTomato)/non-Gad2~(ZsGreen)工具鼠实现GABA能神经元特异性标记 基于Cre-LoxP技术新建Gad2~(tdTomato)/non-Gad2~(ZsGreen)工具鼠实现GABA能神经元特异性标记 第四军医大学口腔医院军事口腔医学国家重点实验室γ-氨基丁酸(γ-......
Using mouse genetic engineering, we have initiated the first round of a systematic effort to genetically target cortical GABAergic neurons. Here, we report the generation and characterization of nearly 20 knockin “driver lines” expressing Cre or inducible CreER recombinase. These mouse lines ...
3绿疫病DK:AAECAfHhBAb47ASk7wTipAWT+wXt/wXMsAYM8OME/+MEhfYEh/YEmYEF9fcFgvgF8vgF6/8FzpwGkZ4GkqAGAAA= 30急速过牌宇宙战:AAECAQcQ5bAEjLcEjtQEkNQEnNQE/+EEj5UF4qQF/cQFxscFkPsFpPsF95cGz54Gr6gG0LAGB5+fBIagBLT4BaH7Bc6cBpyeBp+eBgABA7jZBP3EBf/hBP3EBdGeBv3EBQAA#炉石传说#游戏日常#卡组...
基于Cre-LoxP技术新建Gad2^(tdTomato)/non-Gad2^(ZsGreen)工具鼠实现GABA能神经元特异性标记 病理性改变神经系统疾病中枢神经系统功能异常GABA能神经元转基因小鼠特异性标记抑制性神经元γ-氨基丁酸(γ-aminobutyric acid,GABA)能神经元是哺乳动物中枢神经系统重要的抑制性神经元,其功能异常被证明参与多种神经系统病理...
GABAergic RIP-Cre neurons in the arcuate nucleus selectively regulate energy expenditure. Cell. 2012; 151:645-657. [PubMed: 23101631]Kong D, Tong Q, Ye C, et al. GABAergic RIP-Cre neurons in the arcuate nucleus selectively regulate energy expenditure. Cell 2012;151:645-657...
Fast glutamate and GABA transmission in Crh-IRES-Cre;Ai14 tdTomato neurons.Jaclyn I. Wamsteeker CusulinTamás FüzesiAlan G. WattsJaideep S. Bains
A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. Neuron 71: 995-1013, 2011.Taniguchi H, He M, Wu P, Kim S, Paik R, Sugino K, Kvitsiani D, Kvitsani D, Fu Y, Lu J, Lin Y, Miyoshi G, Shima Y, Fishell G, Nelson SB, Huang ZJ. ...