Gaba-rezeptor-modulatoren Gaba receptor-modulatorsBruce BolgerWellman GeeTsai-Yun LanDelia BelelliSyed MirsadeghiHyde PurdyHasan TahirRavindra B Upasani
GABA-RezeptorChapter pp 83–84 Cite this chapter Anästhesie in Frage und Antwort Georg Petroianu & Peter Michael Osswald 20 Accesses Zusammenfassung Am GABA-Rezaptorkomptex entfaltet/en seine (ihre) Wirkung 1. Benzodiazepine (BDZ) 2. β-Carboline 3. Barbiturate 4. Alkohol 5. ...
a range of substituents at the 3-position and an optional alkyl or cycloalkyl substituent at the 5-position, are selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention...
lower alkoxy, hydroxy, cyano, trifluoromethyl, trifluoromethoxy or lower alkylthio; R2 is -C(O)O-lower alkyl, isoxazol, 1,2,4-oxadiazol-3-yl or 1,2,4-oxadiazol-5-yl, which rings may be substituted by lower alkyl, trifluoromethyl or cycloalkyl; R3 is hydrogen, lower alkyl, -(CH驴2?
BARNES ANTONYWISE ALANMARSHALL HAMILTONFRASER JAMESWHITE HELENFOORD MICHAEL
or substituted by lower alkyl, -(CH2)n-NH-cycloalkyl, lower alkenyl-cycloalkyl, lower alkynyl-(CR'R'')mOH, or lower alkynyl-phenyl wherein the phenyl ring is unsubstituited or substituted by halogen, CF3, lower alkyl or lower alkoxy; R' is hydrogen or lower alkyl; R'' is hydrogen,...
imidazo (1.5). pyrimido) 5.4 - d! benz azepinderivate as gaba a rezeptormodulatorenThe present invention is a compound of formulawhereinR<1 >is halogen or lower alkyl;R<2 >is hydrogen, lower alkyl, cycloalkyl, -(CH2)m-phenyl, wherein the phenyl ring may be substituted by lower alkoxy...
Imidazotriazin-derivate als gaba-rezeptor-liganden Imidazotriazin derivatives as gaba receptor-ligandWilliam Robert CarlingDavid James HallettMichael Geoffrey Neil Russell
Imidazotriazinderivate als gaba rezeptor-liganden Imidazotriazinderivate as gaba receptor-ligandWilliam Robert Harlow CARLINGAlexander Richard Harlow GUIBLINKevin William Harlow MOOREChristopher Richard Harlow MOYESMichael Harlow ROWLEY
2-HYDROXY-PROPIONSÄURE-DERIVATE UND 3-HYDROXY-BENZOFURAN-2-ON-DERIVATE MIT AFFINITÄT FÜR DEN GABA-B-REZEPTORThe present invention relates to compounds of formula I, wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification and claims, which compounds are active on ...