Due to its low lipophilicity, there has been an intensive search for new molecules with increased lipophilicity to cross the blood-brain barrier to raise GABA concentrations. We have designed and evaluated in vitro and in silico some new analogues of GABA, where the nitrogen atom at the γ-...
“In the past years, my regular clientele has grown and has rewarded me with their trust, because these are not just bags, they are investments. Much like jewelry, a lot of the customers I cater to maintain their bags in top condition to get a fair re-sale value, should they decide t...