Interphase Is A Term Used In Biology To Describe The Stage Of The Cell Cycle Between Cell Divisions. It Is A Crucial Period Where The Cell Prepares For Division By Growing Replicating Its DNA And Carrying Out Various Metabolic Activities. During Interphase The Cell Undergoes Three Distinct Phases...
It is well established that the radio-sensitivity is dependent of cell cycle progression, and among the each stage of interphase, G2 phase is the most radiosensitive, G1 phase is the second radiosensitive, S phase is the last radiosensitive...
Also recognized as the “Circle of Life”, the cell cycle can be divided into two distinct stages. The first stage is Interphase which consists of the G1, S, and G2 phases where cells are active, growing, and DNA replication takes place. The second is M-phase, also known as the “...
The accumulation of misfolded proteins, encoded by genetic variants of functional genes leads to Endoplasmic Reticulum (ER) stress, which is a critical consequence in human disorders such as familial hypercholesterolemia, cardiovascular and hepatic disea
stage, the presence of positive regional lymph nodes, as well as distant metastasis in head and neck squamous cell carcinoma [100]. Aurora A also promotes cell migration and reduces the radiosensitivity of laryngeal squamous cell carcinoma [103]. In ovarian cancer, overexpression of Aurora A is ...
(d) Cell lysates from nocodazole-treated HMLE-SNAIL cells were analysed by immunoblotting for FOXC2, PLK1 and p-H3, a marker of mitotic cells. β-actin was used as a loading control. The cell cycle stage, at which cells were arrested by nocodazole, is indicated below the blot. Number ...
Critical at this stage is the crosstalk between ATM and ATR, which has an adaptable component that responds to the DSB load and which has a connection to the cell cycle through Chk1 - and possibly other kinases. Notably, similar connections between resection and checkpoint and a defining role...
stage, the presence of positive regional lymph nodes, as well as distant metastasis in head and neck squamous cell carcinoma [100]. Aurora A also promotes cell migration and reduces the radiosensitivity of laryngeal squamous cell carcinoma [103]. In ovarian cancer, overexpression of Aurora A is ...
(Fig. 3E–L), indicating fertilization enhances its expression throughout embryogenesis process. In the suspensor, EGFP fluorescence was strong at the early stage of development (Fig. 3H–K), but quickly disappeared from the 32-celled globular embryo onward, coinciding with the termination of ...
We noted the existence of a significant correlation between tumor KCTD12 expression levels and tumor size, as well as pathologic T stage, in the 88 lung cancer patients who underwent pre-therapy surgery (Table 1). More importantly, we noted that patients with high tumor KCTD12 expression ...