During the G1 (gap 1) phase, cells grow continuously and prepare for DNA replication. During this phase, cells are metabolically active and copy essential organelles and biochemical molecules, such as proteins. In the subsequent S (synthesis) phase of interphase, cells duplicate their nuclear DNA...
在S期复制后,细胞的DNA含量增加到4n,细胞保持4n直到胞质分裂,此时DNA含量减少到2n。 建议阅读 Tags InterphaseEukaryotic CellsG1SG2Gap PhaseSynthesis PhaseDNA DuplicationChromatinCentrosomesMitotic Spindle ApparatusOrganellesProteinsMitosisCell CycleGrowthReplication Of DNACytokinesis...
The kinase activity towards Thr14 and Tyr15 of the Cdk1 protein is high in interphase and decreases due to hyperphosphorylation in M-phase. In contrast to WEE1, PKMYT1 exhibits more restricted substrate specificity, in that it phosphorylates Cdk1 but not Cdk2 complexes. The direct Cdk1/Cyc...
Moreover, a significant reduction in both G1 and S-phase cell populations (44.41 to 12.66% and 11.82 to 6.65%, respectively) was observed (Figure 2C). Furthermore, 7HF increased the total apoptotic cell population (1.7 to 54%) and gradually reduced the viable cell population (98.05 to ...