G-Motif Oligonucleotides and Uses Thereof 发明人: KLAUS HEEG;GRAYSON LIPFORD;HERMANN WAGNER 申请人: 申请日期: 2004-08-10 申请公布日期: 2004-09-02 代理机构: 代理人: 地址: 摘要: 二、法律状态 暂无信息 三、权利要求 暂无信息 四、说明书暂无信息 打开APP,查看更多专利的权利要求、说明书更多...
These data indicate that an intact proline residue and an intact G14XXXG18 motif within the amino-terminal hydrophobic region of VacA are essential for membrane channel formation, and they also provide strong evidence that membrane channel formation is essential for VacA cytotoxicity....
Considered in this context, the GxxxG sequence motif can be regarded as a framework for the dimerization of transmembrane α-helices. The flat surface provided by the glycine residues can serve as a template for many possible combinations of side-chains at other interfacial positions that act as...
Here we synthesized pentapeptides having a GXXXG motif to explore its role in pore stability. We used molecular dynamics simulations, quantum mechanics, and experimental biophysical techniques to determine whether hydrogen bonding was formed and had a stabilizing function in ion-channel-like structures....
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18. GXXXG motifs are found in transmembrane proteins as helices19and also in soluble proteins where they aid in helix-helix interactions20. The replacement of glycine residue(s) in GXXXXG motif with alanine and valine residue(s) did not evoke significant effect on the cytotoxicity of chrysoph...
Alzheimer’s disease (AD) is the leading cause of dementia in the elderly. Although the pathological features of AD, including excessive amyloid deposits, neurofibrillary tangles, neuroinflammatory responses, and progressive neuronal loss, have been rela
GXXXG motif in the first transmembrane segment of JEV prM protein affected the prM-E heterodimerization; its specificity was confirmed by replacing the two glycines of the GXXXG motif with alanine, leucine and valine. The GXXXG motif was found to be conserved in the JEV serocomplex viruses ...
Recombinant RNA Binding Motif Protein 20 (RBM20) Basic information More.. Product Name: Recombinant RNA Binding Motif Protein 20 (RBM20) Synonyms: Recombinant RNA Binding Motif Protein 20 (RBM20) CAS: MF: MW: 0 EINECS: Mol File: Mol File Information Error Report Your Email: Browse ...
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