Monofunctional gold nanoparticles: synthesis and applications The ability to control the assembly of nanoparticle building blocks is critically important for the development of new materials and devices. The propertie... Q Huo,JG Worden - 《Journal of Nanoparticle Research》 被引量: 59发表: 2007年 ...
DNA Anthraquinone monomerG‐Quadruplex aptamerThermal stabilityMolecular modelingAnti‐thrombin activity1,4-Dihydroxyanthraquinone and 1,8-dihydroxyanthraquinone were alkylated with 3-bromopropan-1-ol and subsequently transformed into the corresponding DMT protected phosphoramidite building blocks for insertion into...
The cell cycle is generally divided into four stages: the G1, S, G2 and M phases [82]. TheG1 phasemainly involves the synthesis of RNA and ribosomes, which are prepared for DNA replication; the S phase mainly includes DNA synthesis and replication; the G2 phase mainly involves the sy...
分子量:141.21类别:Building Blocks; Miscellaneous;应用:2-Azido-3-methylhexane is an intermediate for the synthesis of 3-Methyl-2-hexanamine (M263665), which is an intermediate in the synthesis of Plumbagin-d3 (P627002). Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis ...
p53 levels rise, leading to accumulation of its transcriptional targets including p21/WAF1/CIP1, which binds to and inhibits CDKs and blocks progression through the cell cycle. If the cell arrives in G1 with damaged DNA and high p21/WAF1/CIP1 it will not progress further and will be ...
Synthesis and Molecular Modeling of Thermally Stable DNA G-Quadruplexes with Anthraquinone Insertions Two new phosphoramidite building blocks for DNA synthesis were synthesized from 1,5- and 2,6-dihydroxyanthraquinones via alkylation with 3-bromo-1-propanol... AS Gouda,MS Amine,EB Pedersen - 《Europ...
Synthesis and Molecular Modeling of Thermally Stable DNA G-Quadruplexes with Anthraquinone Insertions Two new phosphoramidite building blocks for DNA synthesis were synthesized from 1,5- and 2,6-dihydroxyanthraquinones via alkylation with 3-bromo-1-propanol... AS Gouda,MS Amine,EB Pedersen - 《Europ...
Members of most of the REP families identified are spread throughout the genome. A noticeable exception is represented byT. roseumGTAG-23 elements, which are clustered in large blocks at few loci. Most REPs are located in the intergenic space. Relative to the orientation of flanking ORFs, repe...
The replication machinery (or replisome), first assembled on both forks at oriC, contains the DnaB helicase for strand separation, and the DNA polymerase III holoenzyme (Pol III HE) for DNA synthesis. DnaB interacts transiently with the DnaG primase for RNA priming on both strands. The Pol ...
S. Mismatch repair blocks expansions of interrupted trinucleotide repeats in yeast. Mol. Cell 6, 1501–1507 (2000). Article CAS PubMed Google Scholar Download references Acknowledgements We thank the US National Institutes of Health, the American Cancer Society and the German Research Organization ...