Within this paper, we analyze the cellular and molecular responses in human monocyte-derived dendritic cells when exposed to virus-like particles (VLPs) with the SARS-CoV-2 spike protein's receptor-binding motif, or, as control groups, with Toll-like receptor (TLR)3 and TLR7/8 agonists. ...
It is well established that the gut microbiota has profound effects on bile acid metabolism by promoting deconjugation, dehydrogenation, and dehydroxylation of primary bile acids in the distal small intestine and colon, thus increasing the chemical diversity of bile acids (Midtvedt, 1974; Ridlon et ...
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