【参考文献】 [1] Epithelioid and spindle cell rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusion: report of two cases.Virchows Arch,2020,477:725-732.
To narrow down target genes of FUS/EWSR1-TFCP2 critical for malignant transformation, we also performed RNA-seq with SCP-1 cells transduced with either fusion, the WT fusion partners, or EV. Both fusions, especially EWSR1-TFCP2, had a substantial impact on the transcriptional landscape of S...
Epithelioid and spindle cell rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusion: report of two cases.RhabdomyosarcomaEpithelioid and spindle cell rhabdomyosarcomaTFCP2EWSR1-TFCP2FUS-TFCP2BoneThe WHO Classification of Tumors of Soft Tissue and Bone divides rhabdomyosarcoma (RMS) into alveolar, ...
Diagnostic and Therapeutic Implications of a FUS::TFCP2 Fusion and ALK Activation in a Metastatic Rhabdomyosarcomadoi:10.1002/gcc.23259Csizmok, VeronikaGrisdale, CameronJ.Williamson, LauraM.Lim, HowardJ.Lee, LawrenceRenouf, DanielJ.Jones, StevenJ.M....
Here, we present a case of cutaneous rhabdomyosarcoma with FUS::TFCP2 fusion in a 35-year-old female. Notably, the tumor exhibited a pathologic spectrum, initially resembling sclerosing dermatitis at presentation but progressing into a high-grade malignant tumor within 8 months. The distinctive ...