In the brain, the 5-HT7R exerts a variety of physiological functions, including learning and memory processing [11, 12]. There is also strong evidence for the involvement of the 5-HT7R in a variety of psychiatric and neurological disorders, such as anxiety, obsessive–compulsive disorder, ...
Neurological disorders: Addiction, ADHD, Alzheimer's Disease, Amnesia, Anorexia Nervosa, Anxiety Disorders, Autism, Bipolar Disorder, Borderline Personality Disorder, Depression, Epilepsy, Huntington's Disease, Obsessive-Compulsive Disorder, Parkinson's Disease, Pedophilia, Posttraumatic SD, Schizophrenia, ...
2,3,4,5. Consequently, mutations in α2δ genes are cause to neurological conditions such as ataxia6,7,8, epilepsy9,10,11,12, and neuropathic pain13,14,15. However, despite numerous reports on the roles of α2δ subunits in HVA channel trafficking16,17...
Neurodegeneration, which refers to the progressive loss of neural tissues and the function of neurons, is associated with a wide range of symptoms, including cognitive impairment, motor deficits, and dementia [8]. Alzheimer’s disease (AD), multiple sclerosis (MS), Parkinson’s disease (PD), a...
neurological diseases [25]. The precise mechanism of FMT treatment for most diseases remains elusive, however, it may be related to the increased microbial abundance and diversity, a higher number of beneficial bacteria, and the enhanced immunological function of the body [26]. Memory deficits and...
Herein, we addressed this question by an analysis of stool samples from the Luxembourg Parkinson’s Study (n = 147 typical PD cases, n = 162 controls). Results All individuals underwent detailed clinical assessment, including neurological examinations and neuropsychological tests followed by ...
The Rho subfamily members of Rho GTPases, RhoA, RhoB, and RhoC, are key regulators of signal transduction in a variety of cellular processes, including regulation of actomyosin and microtubule dynamics, cell shape, cell adhesion, cell division, cell migration, vesicle/membrane trafficking, and ce...
Spastin is a microtubule (MT) severing enzyme that regulates several cell functions associated with MT dynamics. A reduction in spastin protein levels is responsible for approximately 40% of cases of Hereditary Spastic Paraplegia (HSP), a neurodegenerative disease. Currently, there is no cure for ...
et al. Molecular diversity of astrocytes with implications for neurological disorders. Proc. Natl. Acad. Sci. USA 101, 8384–8389 (2004). Article CAS PubMed PubMed Central Google Scholar Cahoy, J.D. et al. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new ...
Walking recovery is among the most desired goals of patients after a neurological injury [12,13]. In order to maximize the recovery of the walking function, an optimal therapeutic plan should be defined and adjusted according to the patient’s progress. However, the lack of quantitative and sen...